APT成像与3D-ASL成像在脑膜瘤分型中的鉴别价值  

Discriminatory value of APT imaging and 3D-ASL imaging in meningioma staging

作　　者：张金环 陈玲[1] 李双红 覃健莉[1] 江宇 彭鹏 李涛[1] ZHANG Jinhuan;CHEN Ling;LI Shuanghong;QIN Jianli;JIANG Yu;PENG Peng;LI Tao(Department of Medical Imaging,The Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou 545007,China;Department of Radiology,The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第四附属医院医学影像科,广西柳州545007 [2]广西医科大第一附属医院放射科,广西南宁530021

出　　处：《医学影像学杂志》2024年第4期1-4,共4页Journal of Medical Imaging

基　　金：广西壮族自治区卫生健康委员会自筹经费科研课题项目(编号:Z20210919);广西壮族自治区柳州市科技计划项目(编号:2021CBC0128)。

摘　　要：目的 探讨酰胺质子转移成像(APT)与三维动脉自旋标记(3D-ASL)在脑膜瘤术前分型中的鉴别价值。方法 选取25例经病理确诊的脑膜瘤患者,术前行3D-ASL、APT及常规MRI检查,分析不同分型脑膜瘤的常规MRI表现,计算并比较各组间脑膜瘤的肿瘤区域血流量(TBF)、相对脑血流量(rCBF)、肿瘤区域APT值、对侧相应位置CBF对侧值、APT对侧值。结果 纤维型脑膜瘤TBF、rCBF值低于内皮型脑膜瘤、过渡型脑膜瘤,且差异均有统计学意义(P=0.009、0.013<0.05);内皮型脑膜瘤与过渡型脑膜瘤之间差异不显著。纤维型脑膜瘤APT值与内皮型脑膜瘤差异具有统计学意义(P=0.040<0.05)。过渡型及内皮型脑膜瘤MRI平扫信号有其特点。结论 APT成像与3D-ASL成像有利于术前鉴别纤维型、内皮型及过渡型脑膜瘤。Objective To study the differential value of amide proton transfer(APT)imaging and three-dimensional arterial spin labeling(3D-ASL)in preoperative staging of meningiomas.Methods Twenty-five patients with pathologically confirmed meningiomas underwent preoperative 3D-ASL,APT and conventional magnetic resonance examinations to analyze the conventional magnetic resonance manifestations of different staging meningiomas.Then,we calculated and compared the tumor regional blood flow(TBF),relative cerebral blood flow(rCBF),tumor regional APT values,contralateral CBF contralateral values,and APT contralateral values of meningiomas at the corresponding locations between groups.Results The TBF and rCBF values of fibrous meningioma were lower than those of endothelial meningioma and transitional meningioma,and the differences were statistically significant(P=0.009 and 0.013<0.05);the differences between endothelial meningioma and transitional meningioma were not significant.The difference between APT values of fibrous meningioma and endothelial meningioma was statistically significant(P=0.040<0.05).Transitional and endothelial meningiomas had their own characteristics of MRI flat scan signal.Conclusion APT imaging and 3D-ASL imaging are useful for preoperative identification of fibrous,endothelial,and transitional meningiomas.

关 键 词：酰胺质子转移成像 三维动脉自旋标记 脑膜瘤 病理分型 磁共振成像 

分 类 号：R739.45[医药卫生—肿瘤] R445.2[医药卫生—临床医学]