环带微结构离焦镜控制青少年近视进展的真实世界研究  

The Efficacy of Ring Microstructure Designed Defocus Lens in Controlling Myopia Progression in Adolescents:A Real Word Study

作　　者：颜月[1] 杨天宇 田彧 杜芬[2] 杨莹莹[2] 陈茹茹 刁凯 王峻峰 陶祥臣[4] 杨积文[5] 卜立敏[5] 刘建军 费亚 谢慧敏 漆文萍[7] 张扬[8] 李军 魏文 葛金玲 李峻[12] 高向红[13] 白莹 马庆凯 郑婕 王鑫 张彦坤[17] 张文亚[18] 王伟娟 吴纲跃 周沛 李永恩 董傲婷 詹绒珍 刘妮 汪超 吉炳闯 刘亚芹[24] 王宇 王欣 李海波 张婵娟 薛维娜 吴玉玲 吴琼 刘陇黔[1] YAN Yue;YANG Tianyu;TIAN Yu;DU Fen;YANG Yingying;CHEN Ruru;DIAO Kai;WANG Junfeng;TAO Xiangchen;YANG Jiwen;BU Limin;LIU Jianjun;FEI Ya;XIE Huimin;QI Wenping;ZHANG Yang;LI Jun;WEI Wen;GE Jinling;LI Jun;GAO Xianghong;BAI Ying;MA Qingkai;ZHENG Jie;WANG Xin;ZHANG Yankun;ZHANG Wenya;WANG Weijuan;WU Gangyue;ZHOU Pei;LI Yongen;DONG Aoting;ZHAN Rongzhen;LIU Ni;WANG Chao;JI Bingchuang;LIU Yaqin;WANG Yu;WANG Xin;LI Haibo;ZHANG Chanjuan;XUE Weina;WU Yuling;WU Qiong;LIU Longqian(West China Hospital,Sichuan University,Chengdu 610044,China;Hunan Children’s Hospital,Changsha 410007,China;Eye Hospital,WMU,Wenzhou 325027,China;Shandong Provincial Hospital,Jinan 250021,China;Aier Eye Hospital(Liaoning),Shenyang 110055,China;Lixiang Eye Hospital of Soochow University,Suzhou 215021,China;Chaoju Eye Hospital(Baotou),Baotou 014016,China;First Affiliated Hospital of Kunming Medical University,Kunming 650032,China;Xi’an NO.1 Hospital,Xi’an 710002,China;Vision Care Center for Younger of Shaanxi Ophthalmological Institute,Xi’an 710004,China;Ji’nan Mingshui Eye Hospital,Ji’nan 250299,China;Siping City Central People’s Hospital,Siping 136099,China;Yan’an University Affiliated Hospital,Yan’an 716099,China;The Sixth People’s Hospital of Chengdu,Chengdu 610051,China;The First Affiliated Hospital of Anhui Medical University.Anhui Branch of National Clinical Research Center for Ocular Diseases,Anhui 230000,China;Shijiazhuang Ophthalmology Department of Hebei Eye Hospital,Shijiazhuang 050035,China;Hebei Chest Hospital,Shijiazhuang 050047,China;Xi’an Huashan Central Hospital,Xi’an 710043,China;Binhai Hospital of Tianjin Medical University General Hospital,Tianjin 300480,China;Jinhua Eye Hospital,Jinhua 321099,China;Hospital of Traditional Chinese Medicine of Dingzhou,Dingzhou 073099,China;Xi’an XD Group Hospital,Xi’an 710077,China;Dongguan People’s Hospital,Dongguan 523058,China;The Second Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710004,China;Huangmei People’s Hospital Vision Centre,Huanggang 435505

机构地区：[1]四川大学华西医院,成都610044 [2]湖南省儿童医院,长沙410007 [3]温州医科大学附属眼视光医院,温州325027 [4]山东省立医院,济南250021 [5]辽宁爱尔眼科医院,沈阳110055 [6]苏州理想眼科医院,苏州215021 [7]包头朝聚眼科医院,包头014016 [8]昆明医科大学第一附属医院,昆明650032 [9]西安市第一医院,西安710002 [10]陕西省眼科研究所青少年近视眼防治中心,西安710004 [11]济南明水眼科医院,济南250299 [12]四平市中心人民医院,四平136099 [13]延安大学附属医院,延安716099 [14]成都市第六人民医院,成都610051 [15]安徽医科大学第一附属医院,眼部疾病国家临床研究中心安徽省分中心,合肥230000 [16]河北省眼科医院石家庄眼科医疗部,石家庄050035 [17]河北省胸科医院,石家庄050047 [18]西安市华山中心医院,西安710043 [19]天津医科大学总医院滨海医院,天津300480 [20]金华眼科医院,金华321099 [21]定州市中医医院,定州073099 [22]西电集团医院,西安710077 [23]东莞市人民医院,东莞523058 [24]西安交通大学第二附属医院,西安710004 [25]黄梅县人民医院视光中心,黄冈435505 [26]天津市北辰医院,天津300134 [27]武汉市第九人民医院视光中心,武汉430034 [28]蕲春县人民医院视光中心,黄冈435399 [29]渭南市第二医院,渭南市眼科医院,渭南714024 [30]盘锦润视儿童眼科医院,盘锦124010 [31]长春一诺眼科医院,长春130028

出　　处：《玻璃搪瓷与眼镜》2024年第5期1-8,共8页Glass Enamel & Ophthalmic Optics

摘　　要：通过大样本量的真实世界研究,对照普通单光镜,利用倾向性评分匹配控制混杂偏倚,通过睫状肌麻痹客观验光屈光度的变化量和眼轴增长量评价环带微结构离焦框架镜——普诺瞳离焦镜在现实临床应用场景下延缓或控制青少年近视的效果。阶段性6个月随访结果显示,普诺瞳离焦镜延缓屈光度进展总有效率为54.9%,延缓眼轴增长总有效率为63.4%,可有效延缓或控制近视进展。Through the real world study with a large sample size,it was conducted to evaluate the efficacy of a ring microstructure designed defocus lens in slowing or controlling myopia in adolescents in realistic clinical settings,which was iBright defocus lens,and the control product was ordinary single vision lens.Propensity score matching(PSM)was used to control confounding bias.The progression of myopia was assessed by the change of axial length and spherical equivalent determined by objective refraction under cycloplegia.The 6-month follow-up results showed that the total effective rate of iBright defocus lens in slowing the progression of spherical equivalent was 54.9%and in slowing the progression of axial length was 63.4%.iBright defocus lens can effectively slow or control the progression of myopia.

关 键 词：离焦镜 等效球镜 眼轴 近视防控 真实世界研究 

分 类 号：R778.11[医药卫生—眼科]