Bioelectronic medicine in modulation of cortical spreading depolarization and beyond  

作　　者：Khaled Alok Timothy G.White Chunyan Li 

机构地区：[1]Department of Neurosurgery,Donald and Barbara Zucker School of Medicine at Hofstra/Northwell,Hempstead,NY,USA [2]Translational Brain Research Laboratory,The Feinstein Institutes for Medical Research,Manhasset,NY,USA

出　　处：《Neural Regeneration Research》2025年第2期481-482,共2页中国神经再生研究（英文版）

基　　金：supported by National Institute of Neurological Disorders and Stroke of the National Institutes of Health under award number R21NS114763;US Army Medical Research and Materiel Command (USAMRMC) under award#W81XWH-18-1-0773;merit-based career enhancement award at the Feinstein Institutes for Medical Research (to CL)

摘　　要：Bioelectronic interventions,specifically trigeminal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurological damage.While pharmacological interventions have demonstrated initial potential in addressing CSDs,a standardized treatment approach has not yet been established.The objective of this perspective is to explore emerging bioelectronic methodologies for addressing CSDs,particularly emphasizing TNS,and to underscore TNS’s capacity to enhance neurovascular coupling and cerebral perfusion.

关 键 词：CEREBRAL PERFUSION electronic 

分 类 号：R338[医药卫生—人体生理学]