胰腺癌疼痛治疗的研究进展  

Research progress in the treatment of pancreatic cancer pain

作　　者：罗凌云 廖云华[1,2] 曹新添 张学学[1,2] LUO Ling-yun;LIAO Yun-hua;CAO Xin-tian;ZHANG Xue-xue(Department of Pain Medicine,The First Affiliated Hospital,Jiangxi Medical College,Nanchang University,Nanchang 330006,China;Key Laboratory of Neuropathic Pain(the First Affiliated Hospital of Nanchang University),Healthcare Commission of Jiangxi Province,Nanchang 330006,China)

机构地区：[1]南昌大学第一附属医院疼痛科,南昌330006 [2]江西省卫生健康委员会神经性疼痛重点实验室,南昌330006

出　　处：《中国疼痛医学杂志》2024年第5期371-376,共6页Chinese Journal of Pain Medicine

基　　金：江西省教育厅科学技术研究项目(GJJ180062);江西省研究生创新基金(YC2021-S206)。

摘　　要：胰腺癌是一种发病隐匿、进展迅速、治疗效果及预后极差的消化道恶性肿瘤,也是全世界排名第11大最常见癌症。疼痛是胰腺癌的主要症状之一,严重影响病人生活质量。目前胰腺癌疼痛治疗应用最为广泛的是药物镇痛。有创操作治疗主要包括腹腔神经、内脏大小神经丛毁损和鞘内给药,可显著降低疼痛,应考虑在癌痛早期阶段应用。本文综合分析了目前临床上胰腺癌疼痛治疗方法,为胰腺癌病人疼痛的最佳治疗方式的选择提供参考。Pancreatic cancer is a malignant tumor of the digestive tract that has an insidious onset,rapid progression,and extremely poor treatment effects and prognosis.It is also the 11th most common cancer in the world.Pain is one of the main symptoms of pancreatic cancer,which seriously affects the patient's quality of life.At present,the most widely used treatment for pancreatic cancer pain is drug analgesia.Invasive surgical treatments mainly include Celiac plexus,splanchnic nerve block,and intrathecal administration,which can significantly reduce pain and should be considered in the early stages of cancer pain.This article comprehensively analyzes the current clinical treatment methods for pancreatic cancer pain,and provides a reference for the selection of the best treatment method for pancreatic cancer patients'pain.

关 键 词：胰腺癌 药物治疗 癌性疼痛 射频消融 神经毁损 

分 类 号：R735.9[医药卫生—肿瘤]