黄曲霉毒素B_(1)对家禽的危害及解毒策略研究进展  

Research Progress on the Harm of Aflatoxin B_(1) to Poultry and Detoxification Strategies

作　　者：杨胜兰 王慧娴 刘金松 杨彩梅 曹广添 YANG Shenglan;WANG Huixiang;LIU Jingsong;YANG Caimei;CAO Guangtian(Zhejiang Agriculture&Forestry University,ZheJiang Hangzhou 311300,China;Zhejiang Vegamax Biotechnology Co Ltd,Zhejiang Huzhou 313306,China;China Jiliang University,Zhejiang Hangzhou 310018,China)

机构地区：[1]浙江农林大学动物科技学院.动物医学院,浙江杭州311300 [2]浙江惠嘉生物科技股份有限公司,浙江湖州313306 [3]中国计量大学标准化学院,浙江杭州310058

出　　处：《中国畜牧杂志》2024年第5期62-67,共6页Chinese Journal of Animal Science

基　　金：浙江省重点研发计划项目资助(2021C02008);浙江省领军型创新创业团队项目(2020R01015)。

摘　　要：黄曲霉毒素是饲料原料中常见的霉菌毒素,这种毒性极强的物质对家禽养殖业危害巨大,可造成机体生长性能下降与免疫抑制,肝脏严重损伤,甚至死亡,其中毒性最强的为黄曲霉毒素B_(1)(AFB_(1))。黄曲霉解毒策略种类繁多,大致可归为物理法、化学法、生物法。物理法和化学法操作简单,但解毒不彻底或引起二次污染;生物法因具有绿色高效的特点,是目前最有前途的解毒策略。本文主要介绍了AFB_(1)对家禽生长性能、肠道健康和机体免疫的影响以及黄曲霉毒素物理、化学解毒方法和生物解毒机制,以期减少黄曲霉毒素对家禽生产的影响。Aflatoxin is a common mycotoxin in feed raw materials.This highly toxic substance has great harm to poultry breeding industry,which can cause decreased growth performance,immune suppression,serious liver damage,and even death,among which the most toxic is Aflatoxin B_(1)(AFB_(1)).There are many kinds of detoxification strategies of Aspergillus flavus,which can be roughly classified into physical,chemical and biological methods.Physical and chemical methods are simple to operate,but detoxification is not complete or cause secondary pollution;Biological method is the most promising detoxification strategy at present because of its green and efficient characteristics.This paper mainly introduced the effects of AFB_(1) on poultry growth performance,intestinal health and immunity,as well as the physical and chemical detoxification methods and biological detoxification mechanisms of aflatoxin,in order to reduce the impact of aflatoxin on poultry production.

关 键 词：黄曲霉毒素 家禽 毒理 生物解毒 

分 类 号：S831.5[农业科学—畜牧学]