甲状腺穿刺细胞的诊断及临床病理特点  

Diagnosis and clinicopathological features of thyroid puncture cells

作　　者：王红群 余娜 巩幼洁 Wang Hongqun;Yu Na;Gong Youjie(Department of Pathology,the Third People's Hospital of Bengbu City,Bengbu,Anhui 233000,China;Department of Pathology,the Second People's Hospital of Bengbu City,Bengbu,Anhui 233000,China)

机构地区：[1]蚌埠市第三人民医院病理科,安徽蚌埠233000 [2]蚌埠市第二人民医院病理科

出　　处：《齐齐哈尔医学院学报》2024年第9期857-860,共4页Journal of Qiqihar Medical University

摘　　要：目的 探讨甲状腺细胞涂片的诊断要点。方法 收集118例甲状腺穿刺涂片患者的临床病理资料,分析形态学特点。结果 40例明确诊断甲状腺乳头状癌,平均47岁,女性30例(75.0%),男性10例(25.0%)。诊断依据,有充足的细胞量,细胞涂片均匀,细胞有乳头状癌的特点,见核沟及核内包涵体,呈乳头状排列。有11例涂片患者检测基因BRAFV600E、6例有突变。结论 细胞丰富且见到核沟及核内包涵体是诊断甲状腺乳头状癌的前提,结合影像学检查可以明确诊断,必要时结合基因检测。Objective To explore the diagnosis essentials of thyroid cell smear.Methods The clinicopathological data of 118 patients who received thyroid smear sampling were collected,and the morphological characteristics were analyzed.Results 40 patients were diagnosed with papillary thyroid carcinoma,mean age was 47 years old,including 30 females(75.0%)and 10 males(25.0%).Diagnosis of papillary thyroid carcinoma,with sufficient cell mass,uniform cell smear,and cells presents characteristics of papillary carcinoma,with nuclear sulcus and intranuclear inclusion bodies,arranged in a papillary pattern.Eleven patients were tested for the BRAFV600E gene,and six had mutation.Conclusions Rich in cells,with visible nuclear grooves and intranuclear inclusion bodies are prerequisite for diagnosing papillary thyroid carcinoma.Combining imaging can provide a clear diagnosis,and genetic testing may be carried out if necessary.

关 键 词：甲状腺乳头状癌 细胞学特点 诊断 

分 类 号：R736.1[医药卫生—肿瘤]