液体栓塞剂与传统栓塞材料治疗消化道出血的疗效及安全性对比  

Comparison of the efficacy and safety of liquid embolic agents and conventional embolic materials in the treatment of gastrointestinal bleeding

作　　者：陈坚[1] 连伟 吴迪圣 CHEN Jian;LIAN Wei;WU Disheng(Department of Vascular and Oncology Intervention,Fuzhou First Hospital,Fuzhou 350009,China)

机构地区：[1]福建省福州市第一医院血管与肿瘤介入科,福州350009

出　　处：《上海医药》2024年第9期74-78,共5页Shanghai Medical & Pharmaceutical Journal

摘　　要：目的:对比温度敏感型液体栓塞剂(TSLEA)与传统栓塞材料在治疗消化道出血(GIB)中的安全性及有效性,分析其应用价值。方法:回顾性分析GIB患者临床资料,根据患者术中有无使用TSLEA分成两组并分析两组间的差异。结果:TSLEA组10例,14支责任血管,非TSLEA组24例,31支责任血管。两组技术成功率均为100%,术后平均随访时间16.07月;非TSLEA组临床成功率91.67%,术后并发症发生率8.33%;TSLEA组无明显并发症,临床成功率90.00%。两组间并发症发生率(P=0.888)、临床成功率(P=0.837)差异无统计学意义。结论:TSLEA与传统的栓塞材料相比,技术成功率、临床成功率及并发症发生率相仿,但其可以通过扭曲、纤细的责任血管,是一种良好的栓塞材料。Objective:To compare the safety and efficacy of temperature-sensitive liquid embolic agent(TSLEA)with traditional embolic materials in the treatment of gastrointestinal bleeding(GIB),and to analyze the value of its application.Methods:The clinical data from GIB patients were retrospectively analyzed,and the patients were divided into two groups according to whether or not they used TSLEA intraoperatively and the differences were compared between the two groups.Results:There were 10 cases with 14 responsible vessels in the TSLEA group and 24 cases with 31 responsible vessels in the non-TSLEA group.The technical success rate of both groups was 100%,and the average postoperative follow-up time was 16.07 months.The clinical success rate was 91.67%with the incidence of postoperative complication 8.33%in the non-TSLEA group and 90.00%without significant complications in the TSLEA group.The differences of the incidence of complication and the clinical success rate between the two groups showed no statistical significance(P=0.888,P=0.837).Conclusion:TSLEA has similar technical and clinical success rates and complication incidence compared with traditional embolic materials,but it can pass through twisted and slender duty vessels and is a good material for embolization.

关 键 词：温度敏感型液体栓塞剂 上消化道出血 介入栓塞 

分 类 号：R573.2[医药卫生—消化系统]