Application of total keratometry in ten intraocular lens power calculation formulas in highly myopic eyes  

作　　者：Ling Wei Kaiwen Cheng Wenwen He Xiangjia Zhu Yi Lu 

机构地区：[1]Department of Ophthalmology and Eye Institute,Eye and ENT Hospital of Fudan University,Shanghai 200031,China [2]Key Laboratory of Myopia(Fudan University)Key Laboratory of MyopiaShanghai Key Laboratory of Visual Impairment and Restoration,National Health Commission,Chinese Academy of Medical Science,Shanghai 200031,China [3]State Key Laboratory of Medical Neurobiology,Fudan University,Shanghai 200031,China

出　　处：《Eye and Vision》2024年第2期22-30,共9页眼视光学杂志（英文）

基　　金：supported by research grants from the National Natural Science Foundation of China(Grant Nos.82122017,81870642,81970780 and 81670835);Science and Technology Innovation Action Plan of Shanghai Science and Technology Commission(Grant Nos.19441900700 and 21S31904900);Clinical Research Plan of Shanghai Shenkang Hospital Development Center(Grant Nos.SHDC2020CR4078 and SHDC12019X08);the Fudan University“Outstanding 2025”Program.

摘　　要：Background:The accuracy of using total keratometry(TK)value in recent IOL power calculation formulas in highly myopic eyes remained unknown.Methods:Highly myopic patients who underwent uneventful cataract surgery were prospectively enrolled in this prospective comparative study.At one month postoperatively,standard deviation(SD)of the prediction errors(PEs),mean and median absolute error(MedAE)of 103 highly myopic eyes were back-calculated and compared among ten formulas,including XGboost,RBF 3.0,Kane,Barrett Universal II,Emmetropia Verifying Optical 2.0,Cooke K6,Haigis,SRK/T,and Wang-Koch modifications of Haigis and SRK/T formulas,using either TK or standard keratometry(K)value.Results:In highly myopic eyes,despite good agreement between TK and K(P>0.05),larger differences between the two were associated with smaller central corneal thickness(P<0.05).As to the refractive errors,TK method showed no differences compared to K method.The XGBoost,RBF 3.0 and Kane ranked top three when considering SDs of PEs.Using TK value,the XGboost calculator was comparable with the RBF 3.0 formula(P>0.05),which both presented smaller MedAEs than others(all P<0.05).As for the percentage of eyes within±0.50 D or±0.75 D of PE,the XGBoost TK showed comparable percentages with the RBF 3.0 TK formula(74.76%vs.66.99%,or 90.29%vs.87.38%,P>0.05),and statistically larger percentages than the other eight formulas(P<0.05).Conclusions:Highly myopic eyes with thinner corneas tend to have larger differences between TK and K.The XGboost enhancement calculator and RBF 3.0 formula using TK showed the most promising outcomes in highly myopic eyes.

关 键 词：High myopia Total keratometry Cataract surgery IOL power calculation 

分 类 号：R778.11[医药卫生—眼科]