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作 者:张林[1] 唐若水 张卫[2] 李兵[2] 詹志来 宋佳[1] 傅延龄[1] 张华敏[2] ZHANG Lin;TANG Ruoshui;ZHANG Wei;LI Bing;ZHAN Zhilai;SONG Jia;FU Yanling;ZHANG Huamin(Beijing University of Chinese Medicine,Beijing,100029;China Academy of Chinese Medical Sciences)
机构地区:[1]北京中医药大学,北京市朝阳区100029 [2]中国中医科学院
出 处:《中医杂志》2024年第8期866-869,共4页Journal of Traditional Chinese Medicine
基 金:中国中医科学院科技创新工程(CI2021A03702);北京市级中医药专家学术经验继承项目。
摘 要:汤剂的剂量、服量及服法是影响方剂疗效的重要因素。对《古代经典名方目录(第一批)》中明清时期35首汤剂进行分析,发现其平均剂量折合约65 g,其中71.4%(25/35)的方剂剂量≤60 g,且明代汤剂剂量显著小于清代。结合宋代方剂特点可以看出,明清汤剂受到宋金元时期盛行的煮散剂的影响,部分汤剂记载的药物剂量为一服量而非一日量,这种服法的记载方式在明代更为明显,至清代,药物所载剂量为一日量的情况又逐渐增多。据此认为,在对明清时期经典名方的研究和应用时,需要注意剂量、一服量和日服量的差别,根据其临床实际判断是否需要在原方所载剂量的基础上加倍,以保证临床疗效。The dosage,dose and administration method of decoctions are important factors affecting the efficacy of prescriptions.By analyzing 35 decoction formulas from the Ming and Qing dynasties within the Catalogue of Ancient Classic Famous Formulas(First Batch),it was found that the average dosage was equivalent to about 65 g,of which 71.4%(25/35)of the prescriptions had a dosage≤60 g.And among them,the dosage of decoctions in the Ming dynasty was significantly smaller than that in the Qing dynasty.Considering the characteristics of formulas in Song dynasty,it is believed that decoctions in Ming and Qing dynasties were influenced by the popular use of decoctions during the Song,Jin,and Yuan dynasties.Some decoctions recorded a dosage of one dose instead of one day,which was more evident in the Ming dynasty.However,by the Qing dynasty,the usage of prescriptions with a dosage of one day gradually became more common.Therefore,in the practical research and application of classic famous formulas from the Ming and Qing dynasties,it is advised to pay attention to the difference between the dosage,one dose and the daily dosage.It is necessary to determine whether to double the dosage of the original formula based on the actual use,in order to ensure the clinical efficacy.
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