不同泌乳阶段的母乳蛋白质含量系统综述  

A SYSTEMATIC REVIEW ON LONGITUDINAL CHANGES OF PROTEIN CONTENT IN BREAST MILKS IN DIFFERENT LACTATION PERIODS

作　　者：王一然 木其尔 李程 罗元理 张亚迪 赖建强 杨月欣[4,5] 朱婧 WANG Yi-ran;MU Qi-er;LI Cheng;LUO Yuan-li;ZHANG Ya-di;LAI Jian-qiang;YANG Yue-xin;ZHU Jing(Beijing Institute of Nutritional Resources Co.,Ltd.,Beijing 100069;West China School of Public Health,Sichuan University,Chengdu 610041;Capital Medical University,Beijing 100069;China-DRIs Research Group on Human Milk Composition,Beijing 100050;National Institute for Nutrition and Health,Chinese Center for Disease Control and Prevention,Beijing 100050;Key Laboratory of Human Milk Science,Chinese Center for Disease Control and Prevention,Beijing 100050;Institute of Biotechnology and Health,Beijing Academy of Science and Technology,Beijing 100089,China)

机构地区：[1]北京市营养源研究所有限公司,北京100069 [2]四川大学华西公共卫生学院,成都610041 [3]首都医科大学,北京100069 [4]中国DRIs母乳成分研究工作组,北京100050 [5]中国疾病预防控制中心营养与健康所,北京100050 [6]中国疾病预防控制中心母乳科学研究重点实验室,北京100050 [7]北京市科学技术研究院生物技术与健康研究所,北京100089

出　　处：《营养学报》2024年第1期86-94,共9页Acta Nutrimenta Sinica

基　　金：中国营养学会DRIs修订专项基金。

摘　　要：目的基于文献数据对母乳总蛋白质含量在不同泌乳期和特殊状况下的变化进行系统分析,为制定中国婴儿蛋白质的需要量提供数据支持。方法通过对5个英文数据库和3个中文数据库进行系统检索,根据纳入排除标准对文献进行筛选,根据泌乳期对同一实验方法测定的母乳总蛋白质含量进行数据提取与合并计算。结果纳入英文文献62篇,中文文献16篇,包含健康乳母足月儿中国母乳样本文献15篇,国外母乳样本文献51篇,早产儿中国母乳样本文献2篇,国外母乳样本文献10篇,共纳入中国母乳样本1816份和国外母乳样本6002份进行合并计算。中国母乳样本和国外母乳样本中蛋白质含量均随哺乳阶段推进逐步降低。结论本研究得到多个文献报道数据合并后不同泌乳期的健康乳母足月儿母乳和早产儿母乳中蛋白质含量的均值和标准差,为制定我国婴儿蛋白质的需要量提供数据支持。Objective To systematically review the changes of total protein levels in different lactation periods and special cases in breast milk,and provide data support for exploring Chinese infants'protein requirements.Methods Systematic retrieval of literatures was performed from 5 English databases and 3 Chinese databases.The data were filtering by the inclusion and exclusion criteria,and data extraction and merging were conducted by lactational periods when the same experimental method was used for determining the total protein content in breast milk.Results A total of 62 English articles and 16 Chinese articles were included,in which 15 articles of Chinese term milk samples,51 articles of foreign term milk samples,2 articles of Chinese preterm milk samples and 10 articles of foreign preterm milk samples were collected.In total,1816 Chinese milk samples and 6002 foreign milk samples were used for data merging.The protein levels in Chinese milk samples and foreign milk samples were gradually decreased throughout lactation stages.Conclusion The mean and standard deviation of protein levels of term and preterm breast milk in different lactational periods were calculated,Which contribute to study on infants'protein requirements in China.

关 键 词：母乳 蛋白质 足月儿 早产儿 

分 类 号：R153.1[医药卫生—营养与食品卫生学]