瑞马唑仑联合腹横肌平面阻滞在腹腔镜结直肠癌根治术麻醉中的效果观察  

Effect of Remimazolam Combined with Transversus Abdominis Plane Block on Anesthesia for Laparoscopic Radical Resection of Colorectal Cancer

作　　者：刘劲 李辰[1] 谢小娟[1] LIU Jing;LI Chen;XIE Xiao-juan(First Affiliated Hospital of Henan University of Science and Technology,Luoyang,Henan 471000)

机构地区：[1]河南科技大学第一附属医院,河南洛阳471000

出　　处：《中国肛肠病杂志》2024年第4期31-33,共3页Chinese Journal of Coloproctology

摘　　要：目的:观察瑞马唑仑联合腹横肌平面阻滞在腹腔镜结直肠癌根治术麻醉中的效果。方法:将2021年1月至2023年6月本院收诊的78例结直肠癌患者随机分为观察组和对照组,每组39例。2组患者均行腹腔镜结直肠癌根治术,观察组患者于麻醉诱导后行瑞马唑仑联合双侧腹横肌平面阻滞(TAPB),对照组患者行双侧TAPB,比较2组患者血压心率变化、术后恢复、不良反应情况与疼痛程度。结果:麻醉前2组患者血压、心率比较差异无统计学意义(P>0.05),切皮后30 min血压、心率均高于麻醉前(P<0.05),但观察组低于对照组(P<0.05);观察组患者术后首次排气时间、住院时间以及下床活动时间均明显短于对照组(P<0.05);观察组患者术后不良反应发生率略低于对照组,但比较差异无统计学意义(P>0.05),术后6 h、12 h观察患者疼痛评分均低于对照组(P<0.05)。结论:瑞马唑仑联合腹横肌平面阻滞可以提高患者术后生理功能恢复,缩短住院时间,且术后镇痛效果好,不良反应少。Objective To observe the effect of remimazolam combined with transversus abdominis plane block(TAPB)on anesthesia for laparoscopic radical resection of colorectal cancer.Methods Total 78pa-tients with colorectal cancer admitted to our hospital from January 2021to June 2023were randomly divid-ed into observation group and control group,with 39cases in each group.The patients in both groups were undergoing laparoscopic radical resection of colorectal cancer.The patients in the observation group were given remimazolam combined with bilateral TAPB after anesthesia induction,while the patients in the con-trol group were given bilateral TAPB.The changes of blood pressure and heart rate,postoperative recover-y,adverse reactions and pain degree of the two groups were compared.Results There was no significant difference in blood pressure and heart rate between the two groups before anesthesia(P>0.05).The blood pressure and heart rate 30min after skin incision were higher than those before anesthesia(P<0.05),which were lower in the observation group than in the control group(P<0.05).The first exhaust time,hospital stay and time to get out of bed after operation in the observation group were significantly shorter than those in the control group(P<0.05).The incidence of postoperative adverse reactions in the observation group was slightly lower than that in the control group,but there was no significant difference(P>0.05).The pain scores of the observation group 6hand 12hafter operation were lower than those of the control group(P<0.05).Conclusion Remimazolam combined with TAPB can improve the recover-y of postoperative physiological function and shorten the length of hospital stay,which has better postoper-ative analgesia effect and fewer adverse reactions.

关 键 词：结直肠癌 根治术 瑞马唑仑 腹横肌平面阻滞 

分 类 号：R735.3[医药卫生—肿瘤]