美沙拉嗪联合中药保留灌肠治疗溃疡性结肠炎疗效观察  

Clinical Efficacy of Mesalazine Combined with Chinese Medicinal Retention Enema in Treating Ulcerative Colitis

作　　者：黄洪涛[1] 赵莉[1] 赵红红 温付东 王靖[1] 王绪文 刘艳[1] HUANG Hong-tao;ZHAO Li;ZHAO Hong-hong;WEN Fu-dong;WANG Jing;WANG Xu-wen;LIU Yan(Department of Anorectal Surgery,Suining Third People's Hospital,Suining,Sichuan 629000)

机构地区：[1]四川省遂宁市第三人民医院肛肠科,四川遂宁629000

出　　处：《中国肛肠病杂志》2024年第3期43-45,共3页Chinese Journal of Coloproctology

基　　金：遂宁市中医药管理局资助项目(SN2021B09)。

摘　　要：目的:分析美沙拉嗪联合中药保留灌肠治疗溃疡性结肠炎的临床疗效。方法:将2021年4月至2023年5月,本院收治的60例溃疡性结肠炎患者采用随机数字表法分为治疗组和对照组,每组各30例。对照组采用美沙拉嗪肠溶片口服,治疗组在对照组基础上联合中药保留灌肠。比较2组治疗效果。结果:治疗后,治疗组总有效率显著高于对照组(90.0%VS 83.3%),差异有统计学意义(P<0.05);治疗组中医证状积分为(4.73±3.98)分,低于对照组的(6.93±4.45)分,差异有统计学意义(P<0.05)。结论:美沙拉嗪联合中药保留灌肠治疗溃疡性结肠炎效果显著,不良反应少,值得临床推广应用。Objective To analyze the clinical efficacy of mesalazine combined with Chinese medicinal retention enema in the treatment of ulcerative colitis(UC).Methods Total 60 patients with UC admitted to our hospital from April 2021 to May 2023 were divided into the treatment group and the control group by random number table method,with 30 cases in each group.The control group was given Mesalazine Enteric-Coated Tablet orally,and the treatment group was combined with Chinese medicinal retention enema on the basis of the control group.The clinical efficacy of the two groups was compared.Results After treatment,the total effective rate of the treatment group was significantly higher than that of the control group(90.0%VS 83.3%),the difference was statistically significant(P<0.05).The TCM syndrome score of the treatment group was(4.73±3.98)points,which was lower than(6.93±4.45)points of the control group,and the difference was statistically significant(P<0.05).Conclusion Mesalazine combined with Chinese medicinal retention enema is effective in the treatment of ulcerative colitis with fewer side effects,which is worthy of clinical promotion and application.

关 键 词：溃疡性结肠炎 美沙拉嗪 中药保留灌肠 疗效 

分 类 号：R574.62[医药卫生—消化系统]