产前MRI对胼胝体缺如及颅内伴随异常的评价  

Evaluation of corpus callosum absence and intracranial accompanying abnormalities via prenatal MRI

作　　者：王婷 李光民[1] 石丽莉[1] 宋鹏飞 赵阳[1] 李素荣[1] WANG Ting;LI Guangmin;SHI Lili;SONG Pengfei;ZHAO Yang;LI Surong(Department of Radiology,Tangshan Maternal and Child Health Hospital,Tangshan,Hebei Province 063003,China)

机构地区：[1]唐山市妇幼保健院放射科,河北唐山063003

出　　处：《实用放射学杂志》2024年第4期531-534,571,共5页Journal of Practical Radiology

摘　　要：目的利用产前MRI评价胎儿胼胝体缺如(ACC)及颅内伴随异常。方法回顾性分析经产前MRI诊断ACC胎儿61例,观察颅内伴随异常的类型及数目,并统计伴随异常的概率,根据胼胝体是否完全缺如分为完全型ACC与部分型ACC,比较2组伴随异常的概率有无统计学差异。结果54.1%(33/61)伴随颅内其他异常,其中脑皮质发育畸形最常见,占26.2%(16/61)。分组分析结果显示完全型ACC与部分型ACC合并颅内其他异常的概率分别为63.4%(26/41)、35.0%(7/20),2组之间存在统计学差异(χ^(2)=4.37,P=0.037)。完全型ACC与部分型ACC合并脑皮质发育畸形的概率分别为39.0%(16/41)、5.0%(1/20),2组之间存在统计学差异(χ^(2)=7.74,P=0.005)。结论MRI可较准确地诊断胎儿ACC及颅内伴随异常。复杂型ACC较独立型ACC常见,完全型ACC与部分型ACC相比合并颅内其他异常的概率大,最常合并脑皮质发育畸形,可为临床评估胎儿预后提供可靠的诊断依据。Objective To evaluate the absence of corpus callosum(ACC)and intracranial accompanying abnormalities in fetus via prenatal MRI.Methods A total of 61 cases of fetal ACC diagnosed by prenatal MRI were analyzed retrospectively.The types and numbers of intracranial accompanying abnormalities were observed,and the probability of accompanying abnormalities was counted.According to whether the corpus callosum was completely absent,all cases were divided into complete ACC and partial ACC.Statistical differences of probability of accompanying abnormalities between the two groups were analyzed.Results A total of 54.1%(33/61)patients were complicated with other intracranial abnormalities,among which the most common was cerebral cortical dysplasia,accounting for 26.2%(16/61).The probability of complete ACC and partial ACC complicated with other intracranial abnormalities was 63.4%(26/41)and 35.0%(7/20),respectively,and there was statistical difference in intracranial abnormalities between complete ACC and partial ACC(χ^(2)=4.37,P=0.037).The probability of complete ACC and partial ACC complicated with cerebral cortical dysplasia was 39.0%(16/41)and 5.0%(1/20),respectively,and there was statistical difference in cerebral cortical dysplasia between complete ACC and partial ACC(χ^(2)=7.74,P=0.005).Conclusion MRI can accurately diagnose the fetal ACC and intracranial accompanying abnormalities.Complex ACC is more common than isolated ACC.Compared with partial ACC,complete ACC is more likely to be complicated with other intracranial abnormalities,and cerebral cortical dysplasia is the most common,which provides reliable diagnostic basis for fetal prognosis in clinical practice.

关 键 词：胎儿 胼胝体缺如 磁共振成像 

分 类 号：R714.431[医药卫生—妇产科学] R445.2[医药卫生—临床医学]