实体器官移植患者的口腔种植治疗研究进展  

Research progress of dental implants in patients with solid organ transplantation

作　　者：赵克[1,2] 朱洁莹 顾新华 Zhao Ke;Zhu Jieying;Gu Xinhua(Department of Stomatology,The First Affiliated Hospital of Zhejiang University School of Medicine,Hangzhou 310003,China;Department of Stomatology,Zhejiang University School of Medicine,Hangzhou 310058,China)

机构地区：[1]浙江大学医学院附属第一医院口腔科,杭州310003 [2]浙江大学医学院口腔医学院,杭州310058

出　　处：《中国口腔种植学杂志》2024年第2期190-194,共5页Chinese Journal of Oral Implantology

摘　　要：随着实体器官移植治疗技术的发展,患者的生存期逐渐延长,对恢复缺失牙的需求也逐渐增加。在长期的临床实践中,种植治疗可作为恢复患者口颌功能的一种安全、有效方案。然而,许多原发疾病及移植后终身的免疫抑制治疗对骨代谢的影响,增加了骨质疏松、骨折等疾病的风险,同时也为骨与种植体的结合带来了潜在危害。因此,移植后全身情况的稳定、种植围手术期口腔内感染的控制、种植体负荷时间以及定期随访检查在此类患者的种植治疗中尤为重要。本文将就实体器官移植对骨及种植体骨结合的影响、口腔种植治疗进展及注意事项等方面进行阐述,以期为临床医生提供参考。With the development of solid organ transplantation treatment technology,the survival period of patients is gradually extended,and the demand to restore missing teeth is increasing.In long-term clinical practice,implant therapy can be used as a safe and effective program to restore stomatognathic function.However,the impacts of primary disease and lifelong immunosuppressive therapy after transplantation on bone metabolism increase the risk of osteoporosis,fracture,and other diseases,and bring potential hazards to implant osseointegration.Therefore,stability of condition after transplantation,control of oral infection during the perioperative period of implantation,implant loading time,and regular follow-up examination are particularly important in the implantation treatment of such patients.In this review,we discuss the effects of solid organ transplantation on bone and implant osteoporosis,the progress and precautions of oral implant treatment,so as to provide guidance for dentists.

关 键 词：实体器官移植 免疫抑制剂 种植 

分 类 号：R783.6[医药卫生—口腔医学] R617[医药卫生—临床医学]