Surface demineralized freeze-dried bone allograft followed by reimplantation in a failed mandibular dental implant  

作　　者：Jing Zhang Jie Wang Jiayi You Xuan Qin Huimin Chen Xiantong Hu Yantao Zhao Yang Xia 

机构地区：[1]Jiangsu Key Laboratory of Oral Diseases,Nanjing Medical University,Nanjing,Jiangsu 210029,PR China [2]Jiangsu Province Engineering Research Center of Stomatological Translational Medicine,Nanjing Medical University,Nanjing,Jiangsu 210029,PR China [3]Department of Restorative Dental Sciences,Faculty of Dentistry,The University of Hong Kong,Hong Kong SAR,PR China [4]Senior Department of Orthopedics,The Fourth Medical Center of PLA General Hospital,Beijing,100048,PR China [5]Beijing Engineering Research Center of Orthopedics Implants,Beijing 100048,PR China [6]State Key Laboratory of Military Stomatology,Xi'an 710032,PR China

出　　处：《Regenerative Biomaterials》2024年第1期82-93,共12页再生生物材料（英文版）

基　　金：supported by grants from the Natural Science Foundation of Jiangsu Province(Grant number BK20211249);the Beijing Science Nova Program(Grant number 20220484155);the Haidian Frontier Project of Beijing Natural Science Foundation(Grant number L212067);the Jiangsu Province Capability Improvement Project through Science,Technology and Education-Jiangsu Provincial Research Hospital Cultivation Unit(Grant number YJXYYJSDW4);the Jiangsu Provincial Medical Innovation Center(Grant number CXZX202227).

摘　　要：The removal of a failed implant with high torque causes significant damage to the surrounding tissue,compromising bone regeneration and subsequent osseointegration in the defect area.Here,we report a case of carrier screw fracture followed by immediate implant removal,bone grafting and delayed reimplantation.A dental implant with a fractured central carrier screw was removed using the bur-forceps technique.The resulting three-wall bone defect was filled with granular surface demineralized freeze-dried bone allograft(SD-FDBA).Cone-beam computerized tomography was performed at 1week,6months and 15months postoperatively and standardized for quantitative evaluation.The alveolar bone width and height at 15months post-surgery were about 91%of the original values,with a slightly lower bone density,calculated using the gray value ratio.The graft site was reopened and was found to be completely healed with dense and vascularized bone along with some residual bone graft.Reimplantation followed by restoration was performed 8months later.The quality of regenerated bone following SD-FDBA grafting was adequate for osseointegration and longterm implant success.The excellent osteogenic properties of SD-FDBA are attributed to its human origin,cortical bone-like structure,partly demineralized surfaces and bone morphogenetic protein-2-containing nature.Further investigation with more cases and longer follow-up was required to confirm the final clinical effect.

关 键 词：dental implant implant failure allogeneic bone bone regeneration REIMPLANTATION 

分 类 号：R78[医药卫生—口腔医学]