非良性脑膜瘤与良性脑膜瘤临床与影像征象对比研究  

Comparative Study of Clinical and Imaging Signs of Non⁃Benign Meningioma and Benign Meningioma

作　　者：逯慧珍 李天云 李磊磊 韩博 任可可 黄瑞 王晨 郭钒 LU Huizhen;LI Tianyun;LI Leilei(Department of Radiology,Xijing Hospital,Air Force Medical University,Xi’an,Shaanxi Province 710032,P.R.China)

机构地区：[1]空军军医大学第一附属医院放射科,西安710032 [2]西安市中医医院影像科,710018

出　　处：《临床放射学杂志》2024年第4期500-504,共5页Journal of Clinical Radiology

摘　　要：目的 探讨非良性脑膜瘤(NM)与良性脑膜瘤(BM)的临床、影像学征象。方法 回顾性分析118例经手术证实为脑膜瘤患者的临床资料、影像学结果,根据2021版WHO脑膜瘤组织学分型方法,将患者分为良性(Ⅰ级)组72例和非良性组(Ⅱ~Ⅲ级)46例,所有患者术前均行MRI平扫及增强扫描。采用多因素Logistic回归分析良性组和非良性组脑膜瘤的MRI影像学表现及特点。结果 非良性组与良性组在肿瘤最大径、强化方式、形状、边缘、HSL征、脑侵袭、中性粒细胞百分比(NEUT%)、淋巴细胞百分比(LY%)上比较,差异有统计学意义(P<0.05);多因素Logistic回归分析示肿瘤最大径、形状、边缘、HSL征、脑侵袭是非良性脑膜瘤的独立危险因素(P<0.05)。结论 术前脑膜瘤MRI特征有助于判断脑膜瘤良恶性,可为术前临床治疗方案的确定提供有效临床辅助。Objective To investigate the clinical and imaging signs of non⁃benign meningioma(NM)and benign men⁃ingioma(BM).Methods Clinical data and imaging results of 118 patients with surgically confirmed meningioma were analyzed retrospectively.The patients were divided into 72 cases in the benign group(GradeⅠ)and 46 cases in the non⁃benign group(GradeⅡ-Ⅲ)according to the 2021 WHO meningioma histological subtyping method,who were examined by routine and enhanced MRI.Logistic regression was used to analyze the MRI imaging findings and characteristics of benign and non⁃benign meningiomas.Results Compared with the non⁃benign group,there were statistically significant differences in tumor max diameter,way of enhancement,shape,margin,hypointensity of the surface layer(HSL)sign,brain invasion,NEUT%,LY%(P<0.05);Multivariate Logistic regression analysis showed that tumor max diameter,shape,margin,HSL sign,brain invasion were independent risk factors of non⁃benign meningioma(P<0.05).Conclusion Preoperative MRI features of meningioma are helpful to determine the non⁃benign meningioma,and can be used as effective means to guide clinical treatment.

关 键 词：非良性脑膜瘤 良性脑膜瘤 影像征象 HSL征 

分 类 号：R739.45[医药卫生—肿瘤] R445.2[医药卫生—临床医学]