150例老年肝癌根治性切除术后肝癌复发的高危因素分析  

Analysis of risk factors for recurrence of hepatocellular carcinoma in aged patients with multicentre radical resection

作　　者：赵刚 武青生 马生彪 王巍 穆元忠 谭成军 赵茂成 ZHAO Gang;WU Qing sheng;MA Sheng-biao(General Surgery department,The Fifth People's Hospital of Qinghai Province,Xining 810000,China)

机构地区：[1]青海省第五人民医院普通外科,西宁810000

出　　处：《肝胆外科杂志》2024年第1期45-48,共4页Journal of Hepatobiliary Surgery

基　　金：青海省医药卫生科技项目(2016035)。

摘　　要：目的分析老年肝癌根治性切除术后肝癌复发的高危因素。方法研究对象为老年肝癌患者,这些患者在2017年9月到2020年9月在我院诊治,治疗方面选用了肝癌根治性切除术,数量共计150例。医院对这些患者进行了随访,时间为12个月,可了解患者病情是否复发,如果患者像学检查有明确的肿块,那么可确定肝癌术后复发时间。本文选用多因素进行分析,找出了导致患者术后复发的主要因素。结果患者共计150例,手术后进行随访,随访时间为12个月,患者出现复发的共计29例,复发率达到了19.33%。通过单因素分析得出,两个小组在性别、合并基础疾病、术前ALT、术前AST、手术时间方面没有展现统计学意义(P>0.05);两个小在组肿瘤直径、血管侵犯、肿瘤包膜、术中失血方面展现出了统计学意义(P<0.05)。单因素分析方面展现统计学意义的放入到多因素分析发现,影响老年肝癌根治性切除术后复发危险因素较多,它们是肿瘤直径、血管侵犯、肿瘤包膜、术中失血为。结论通过研究老年肝癌根治性切除术后肝癌复发因素得出,危险性较高影响较多,它们是肿瘤直径、血管侵犯、肿瘤包膜、术中失血为。Objective To analyze the risk factors for recurrence of hepatocellular carcinoma(HCC)in elderly patients with multicentre radical resection.Methods The subjects of this study were elderly patients with liver cancer,who were diagnosed and treated in our hospital from September 2018 to September 2019.A total of 150 patients were treated with radical resection of liver cancer.These patients were followed up in the hospital for 12 months to know whether the disease had recurred or not.If the patients had a definite mass in the medical examination,the time of recurrence after liver cancer surgery could be determined.In this paper,multiple factors were selected for analysis to find out the main factors leading to postoperative recurrence of patients.Results A total of 150 patients were followed up after surgery for 12 months.A total of 29 patients experienced recurrence,with a recurrence rate of 19.33%.Through univariate analysis,the two groups showed no statistical significance in terms of gender,underlying diseases,preoperative ALT,preoperative AST,and operative time(P>0.05).The two groups showed statistical significance in tumor diameter,vascular in-vasion,tumor capsule and intraoperative blood loss(P<0.05).In terms of univariate analysis,there were statistically significant fac-tors influencing the risk of recurrence after radical resection of liver cancer in the elderly,including tumor diameter,vascular invasion,tumor capsule and intraoperative blood loss.Conclusion By studying the recurrence factors of hepatocellular carcinoma after multi-center radical resection in elderly patients,we can conclude that the risk is higher and the influence is more.They are tumor diameter,vascular invasion,tumor capsule and intraoperative blood loss.

关 键 词：老年肝癌根治性切除术 术后复发 高危因素 

分 类 号：R735.7[医药卫生—肿瘤]