特纳综合征高血压的研究进展  

Research progress on association between Turner syndrome and high blood pressure

作　　者：刘继纯 胡思思 葛涛 谢向荣 LIU Jichun;HU Sisi;GE Tao;XIE Xiangrong(Department of Cardiology,The First Affiliated Hospital of Wannan Medical College,Wuhu 241001,Anhui,China)

机构地区：[1]皖南医学院第一附属医院(弋矶山医院)心内科,安徽芜湖241000

出　　处：《中国临床药理学与治疗学》2024年第6期700-706,共7页Chinese Journal of Clinical Pharmacology and Therapeutics

基　　金：安徽省高校科研计划项目(自然科学重点项目)(2022AH051238);安徽省临床重点专科项目(KZSJZ008);皖南医学院校中青年科研基金(WK2023ZQNZ23)。

摘　　要：特纳综合征是临床表型为女性的性染色体病。大部分患者常因生长发育迟缓在儿童或青少年时期被确诊,少部分患者因特纳综合征相关疾病就诊被诊断。特纳综合征的女性在儿童期和青少年时期就可出现高血压,高血压患病率随年龄增长而增加,其发病机制尚不清楚,可能是多因素的,与原发性高血压相似。本综述探讨特纳综合征患者高血压的可能机制、血压管理和治疗建议。Turner syndrome is a sex chromosome disease with a female clinical phenotype.Most pa-tients are diagnosed in childhood or adolescence because of growth delays,and a small number of patients are diagnosed due to TS-related diseases.Women with Turner syndrome can develop hyper-tension in childhood and adolescence,and the prevalence of hypertension increases with age.The pathogenesis is unclear and may be multifactorial,similar to essential hypertension.In this review arti-cle,we explore possible mechanisms,blood pres-sure management,and treatment recommenda-tions for hypertension in patients with Turner syn-drome.

关 键 词：高血压 特纳综合征 性染色体病 

分 类 号：R96[医药卫生—药理学]