放射性口腔黏膜炎的评估、发病机制及预防研究  

Evaluation, Pathogenesis and Prevention of Radiation-induced Oral Mucositis

作　　者：梁雷锋[1] 宋自晓 王仁生 LIANG Lei-feng;SONG Zi-xiao;WANG Ren-sheng(Department of Oncology,the Sixth Affiliated Hospital of Guangxi Medical University/the First people's Hospital of Yulin,Yulin 537000,Guangxi,China)

机构地区：[1]广西医科大学第六附属医院/玉林市第一人民医院肿瘤科,广西玉林537000

出　　处：《医学信息》2024年第11期165-169,共5页Journal of Medical Information

基　　金：国家自然科学基金(编号:82260627)。

摘　　要：放射性口腔黏膜炎(RIOM)是头颈部肿瘤患者放疗过程中最常见的并发症之一,为早期剂量限制性毒性反应,对患者生活质量甚至肿瘤治疗效果产生不利影响。RIOM目前尚无预防和治疗的理想方案。本文就RIOM的流行病学、症状和分级标准、发病机制以及预防措施的进展做一综述,希望能为临床实践中处理RIOM提供参考。Radiation-induced oral mucositis(RIOM)is one of the most common complications in patients with head and neck cancer during radiotherapy.It is an early dose-limiting toxic reaction that adversely affects the quality of life of patients and the effect of tumor treatment.At present,there is no ideal scheme for the prevention and treatment of RIOM.This article reviews the epidemiology,symptoms and grading standards,pathogenesis and preventive measures of RIOM,hoping to provide reference for the treatment of RIOM in clinical practice.

关 键 词：放射性口腔黏膜炎 放疗 头颈部肿瘤 

分 类 号：R781.5[医药卫生—口腔医学]