持续泵入24h艾司奥美拉唑联合内镜下碎石治疗胃结石的临床疗效  

Clinical Efficacy of Continuous 24 h Infusion of Esomeprazole Combined with Endoscopic Lithotripsy in the Treatment of Gastric stones

作　　者：杨滨海 YANG Binhai(Department of Gastroenterology,Binzhou Second People's Hospital,Binzhou 256800,China)

机构地区：[1]滨州市第二人民医院消化内科,滨州256800

出　　处：《中国医药指南》2024年第15期21-23,共3页Guide of China Medicine

摘　　要：目的 探讨持续泵入24h艾司奥美拉唑联合内镜下碎石治疗胃结石的临床疗效。方法 回顾性分析滨州市第二人民医院2019年1月至2022年11月收治的38例胃结石患者的临床资料。以随机数字表法将38例胃结石患者分为观察组(n=20)、对照组(n=18),其中观察组以8 mg/h的速度持续泵入24h艾司奥美拉唑,对照组以艾司奥美拉唑40 mg每日2次静脉滴注,比较两组碎石成功情况、治疗时间和住院时间。结果 观察组中19例(95.00%)患者经一次碎石就成功排出结石,1例(5.00%)需2次碎石成功排出结石。对照组中8例(44.44%)患者经1次碎石后成功排出结石,8例(44.44%)患者需2次碎石成功排出结石,2例(11.11%)患者需3次碎石才能成功排出结石,且观察组一次性治疗成功的频率高于对照组(95.00%vs. 44.44%,P<0.05)。观察组平均手术时间短于对照组(P<0.05);观察组住院时间短于对照组(P<0.05)。结论 持续泵入24h艾司奥美拉唑可以有效提高内镜下碎石治疗率,明显缩短治疗时间和住院时间。Objective To explore the clinical efficacy of continuous infusion of Esomeprazole for 24 hours combined with endoscopic lithotripsy in the treatment of gastric stones.Methods The clinical data of 38 patients with gastric stones admitted to Binzhou Second People's Hospital from January 2019 to November 2022 were retrospectively analyzed.Thirty-eight patients with gastric stones were divided into observation group(n=20)and control group(n=18),the observation group was continuously pumped with esomeprazole at a rate of 8 mg/h for 24 h,and the control group was treated with esomeprazole 40 mg intravenously twice a day,and the success,treatment time and length of hospital stay were compared.Results In the observation group,19 patients(95.00%)successfully passed stones after one lithotripsy,and 1 case(5.00%)needed two lithotripsies to successfully pass stones.In the control group,8 patients(44.44%)successfully passed stones after 1 lithotripsy,8 patients(44.44%)needed 2 lithotripsy to successfully pass stones,and 2 patients(11.11%)needed 3 lithotripsies to successfully pass stones.The frequency of one-time treatment success in the observation group was higher than that in the control group(95.00%vs.44.44%,P<0.05).The average operation time of the observation group was shorter than that of the control group(P<0.05);The hospitalization time of observation group was shorter than that of control group(P<0.05).Conclusions Continuous injection of esomeprazole for 24 h can effectively improve the rate of endoscopic lithotripsis and significantly shorten the duration of treatment and hospital stay.

关 键 词：胃结石 消化系统 内镜下碎石 

分 类 号：R573.8[医药卫生—消化系统]