后循环脑梗死轻症患者早期神经功能恶化的危险因素分析  

Risk factors for early neurological deterioration of patients with mild posterior circulation cerebral infarction

作　　者：钱倩 张静[1] 边伟林 邢晓明[1] 张欣[1] 白艳梅 赵小妹[1] 高娟[1] Qian Qian;Zhang Jing;Bian Weilin;Xing Xiaoming;Zhang Xin;Bai Yanmei;Zhao Xiaomei;Gao Juan(Department of Neurology,Baoding NO.1 Central Hospital,Baoding 071000,China;Department of Radiology,Baoding People's Hospital,Baoding 071000,China)

机构地区：[1]河北省保定市第一中心医院神经内科,071000 [2]河北省保定市人民医院放射科,071000

出　　处：《心脑血管病防治》2024年第4期32-35,共4页CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT

基　　金：河北省卫生健康委科研基金项目(20220288)。

摘　　要：目的探讨美国国立卫生研究院卒中量表(NIHSS)评分≤5分的轻症急性后循环脑梗死(APCCI)患者早期神经功能恶化(END)的危险因素。方法回顾性收集2019年1月至2021年6月期间,保定市第一中心医院收治的入院时NIHSS评分≤5分的APCCI患者116例,根据是否发生END分为END组与非END组。比较两组的一般资料及临床特征,使用Logistic回归模型分析END的影响因素。结果21例发生END,发生率为18.10%。以END为终点事件的多变量Logistic回归分析显示,总胆固醇(TC)水平(OR=1.096,95%CI=1.034~1.158)、基线NIHSS评分(OR=2.263,95%CI=1.085~3.441)、大动脉粥样硬化型(OR=1.187,95%CI=1.043~1.332)、中段梗死(OR=4.012,95%CI=1.579~7.688)和肺部感染(OR=1.285,95%CI=1.164~1.406)是APCCI患者发生END的危险因素(P<0.05)。结论高水平TC、基线NIHSS评分高、大动脉粥样硬化型、中段梗死和合并肺部感染是轻症APCCI患者发生END的危险因素。Objective To investigate the risk factors for early neurological deterioration(END)in patients with mild acute posterior circulation cerebral infarction(APCCI)assessed by National Institute of Health Stroke Scale(NIHSS)score≤5.Methods Data of 116 APCCI patients admitted to Baoding NO.1 Central Hospital from January 2019 to June 2021 were collected,all with NIHSS score≤5 on admission.Patients were divided into END group and non-END group based on END occurrence.General data and clinical characteristics of the two groups were compared,and influencing factors for END were analyzed using Logistic regression model.Results Twenty-one patients experienced END,with an incidence of 18.10%.Multivariate Logistic regression analysis with END as the outcome event showed that total cholesterol(TC)level(OR=1.096,95%CI=1.034-1.158),baseline NIHSS score(OR=2.263,95%CI=1.085-3.441),large-artery atherosclerosis(OR=1.187,95%CI=1.043-1.332),middle segment cerebral infarction(OR=4.012,95%CI=1.579-7.688)and pulmonary infection(OR=1.285,95%CI=1.164-1.406)were risk factors for END in APCCI patients(P<0.05).Conclusion High TC level,high baseline NIHSS score,large-artery atherosclerosis,middle segment cerebral infarction and pulmonary infection are risk factors for END in patients with mild APCCI.

关 键 词：后循环脑梗死 早期神经功能恶化 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]