思睡期典型轴向抽搐的脊髓固有束肌阵挛1例  

A case of propriospinal myoclonus with typical axial convulsions during sleep

作　　者：龚紫薇 王芬[1] 王晔[1,2] GONG Ziwei;WANG Fen;WANG Ye(Department of Neurology,The Second Affiliated Hospital of Nanchang University,Institute of Neuroscience,Nanchang University,Nanchang,330006,China)

机构地区：[1]南昌大学第二附属医院神经内科,南昌330006 [2]南昌大学神经病学研究室

出　　处：《中国神经精神疾病杂志》2024年第3期152-155,共4页Chinese Journal of Nervous and Mental Diseases

基　　金：国家自然科学基金项目(编号:82060254)。

摘　　要：脊髓固有束肌阵挛(propriospinal myoclonus,PSM)是一种以觉醒和睡眠转换期反复出现轴向肌阵挛为特征的罕见无痛性运动障碍疾病,因在思睡期反复发生肌肉抽搐,导致患者的睡眠严重受影响。报告1例典型PSM,患者因入睡前肢体不自主抖动1年余就诊,入院查体未发现明显阳性体征,在完善视频多导睡眠监测及多部位肌电图监测后诊断为特发性PSM,并且对1/3片氯硝西泮治疗反应良好,提示视频多导睡眠监测及多部位肌电图监测在诊断PSM中的必要性。Propriospinal myoclonus(PSM)is a rare painless movement disorder characterized by recurrent axial myoclonus during the wake and sleep transition periods.The recurrent muscle twitches during the hypnotic period severely affect the patient's sleep.In this paper,we reported a case of typical PSM.The patient was treated for involuntary limb shaking before sleep for more than 1 year,and no significant positive signs were found after physical examination in hospital.After perfecting video polysomnography and polymyography,he was diagnosed as having idiopathic PSM,and he responded well to 1/3 of clonazepam tablets,suggesting the necessity of video polysomnography and polymyography in the diagnosis of PSM.

关 键 词：脊髓固有束肌阵挛 睡眠相关运动障碍 多肌图 脊髓节段性肌阵挛 轴向性肌阵挛 

分 类 号：R741[医药卫生—神经病学与精神病学]