白花蛇舌草乙醇提取液在化妆品中的应用  

Application of Ethanol Extract from Hedyotisdiffusa in Cosmetics

作　　者：阮英 Ruan Ying(Fuzhou Renliang Biological Products Co.,Ltd.,Fuzhou 350015,China)

机构地区：[1]福州仁量生物制品有限公司,福建福州350015

出　　处：《云南化工》2024年第5期127-130,148,共5页Yunnan Chemical Technology

摘　　要：通过醇提法对白花蛇舌草进行提取,研究其提取物对酪氨酸酶的影响、抗氧化能力、抗菌作用和保湿性能,评价其在化妆品中的应用。结果表明,白花蛇舌草提取物对酪氨酸酶有抑制作用,当浓度为250μg/mL时抑制率可达71.69%。白花蛇舌草提取液对DPPH自由基有很强的清除作用,半数清除质量浓度为17.62μg/mL。白花蛇舌草提取液对于大肠杆菌、铜绿假单细胞菌和金黄色葡萄球菌均有良好的抑制作用。与甘油相比,白花蛇舌草具有一定的保湿作用,作用来源于对外界水分的吸收。白花蛇舌草拥有良好美白、抗氧化、抗菌及保湿效果,可应用于相应功效化妆品研发中。Hedyotisdiffusa was extracted by alcohol extraction method.The effects of ethanol extract on tyrosinase,antioxidant capacity,antimicrobial and moisturizing properties were studied,and its application in cosmetics was evaluated.The results showed that the extract of Hedyotisdiffusawill inhibit the activity of tyrosinase,which inhibition rate could reach 71.69%at the concentration of 250μg/mL.The extract of Hedyotisdiffusa had a strong scavenging effect on DPPH free radicals,and median clearance mass concentration(EC 50)was 17.62μg/mL.The extract of Hedyotisdiffusa had good inhibitory effects on Escherichia coli,Pseudomonas aeruginosa and Staphylococcus aureus.Compared with glycerol,Hedyotisdiffusa has a certain moisturizing effect,which comes from the absorption of external water.Hedyotisdiffusa has good whitening,antioxidant,antimicrobial and moisturizing effects,which can be applied in the research and development of cosmetics with corresponding efficacy.

关 键 词：白花蛇舌草 抗氧化 酪氨酸酶 抑菌 保湿 

分 类 号：R282[医药卫生—中药学]