发病超24小时急性缺血性卒中机械取栓的研究进展  

Research progress on mechanical thrombectomy for acute ischemic stroke beyond 24 hours of onset

作　　者：石万达 白雪松[2] 孔文程 焦力群[2] 赵彦新[1] Shi Wanda;Bai Xuesong;Kong Wencheng;Jiao Liqun;Zhao Yanxin(Department of Neurology,Central Hospital Affiliated to Shandong First Medical University(Jinan Central Hospital),Jinan 250013,China)

机构地区：[1]山东第一医科大学附属中心医院(济南市中心医院)神经内科,250013 [2]首都医科大学宣武医院神经外科

出　　处：《中国脑血管病杂志》2024年第5期349-354,共6页Chinese Journal of Cerebrovascular Diseases

摘　　要：卒中是目前危及人类建康的重大疾病,自2015年以来,机械取栓已成为急性缺血性卒中的主要治疗手段。目前的指南倾向于机械取栓治疗时间窗在24 h以内的急性缺血性卒中患者,对于超24 h急性缺血性卒中机械取栓是否有效尚存在争议。作者回顾了已报道的相关临床研究,从研究设计的角度分析其安全性及有效性,并对预测因素及影像学筛查方式的选择进行综述。Stroke is a major disease that endangers the health of human beings.Since 2015,mechanical thrombectomy has emerged as the primary therapeutic method for acute ischemic stroke.Present guidelines lean towards treating patients with mechanical thrombectomy within a therapeutic window,while the efficacy of thrombectomy beyond 24-hour remains a matter of contention.The authors manuscript undertook a retrospective review of extant clinical research,scrutinizing its safety and efficacy from the standpoint of research design,and offering a detailed synthesis concerning on predictive factors and imaging modalities for selection.

关 键 词：卒中 血管内治疗 时间窗 半暗带 综述 

分 类 号：R743.3[医药卫生—神经病学与精神病学]