多发腔隙性脑梗死后血管性认知障碍的发生情况及影响因素分析  

Occurrence and influencing factors for vascular cognitive impairment after multiple lacunar cerebral infarction

作　　者：耿玉娟 吴敏[1] 陈凤[1] 曹云[1] GENG Yujuan;WU Min;CHEN Feng;CAO Yun(Jiangsu Provincial People’s Hospital,Nanjing 210000,China)

机构地区：[1]江苏省人民医院,江苏南京210000

出　　处：《中国实用神经疾病杂志》2024年第6期685-690,共6页Chinese Journal of Practical Nervous Diseases

基　　金：2022年度临床能力提升工程护理项目(编号:JSPH-NC-2022-2);江苏省卫生健康委科研项目(编号:H2019108)。

摘　　要：目的探讨多发腔隙性脑梗死后血管性认知障碍发生的独立风险因素。方法采用回归分析研究多发腔隙性脑梗死患者的年龄、文化程度、婚姻状况、民族、吸烟史、饮酒史、运动状况、饮食状况、家族痴呆史、家族高血压史、家族脑卒中史、家族糖尿病史、合并心脏病、合并高血压、合并高血脂、合并糖尿病、脑梗死位置和NIHSS评分对多发腔隙性脑梗死后血管性认知障碍发生的影响。结果450例患者中40例(8.89%)发生血管性认知障碍。年龄、婚姻状况、运动状况、家族痴呆史、家族脑卒中史、合并高血压、合并高血脂、脑梗死位置和NIHSS评分是多发腔隙性脑梗死后血管性认知障碍发生的独立风险因素(P<0.05)。结论年龄、婚姻状况、运动状况、家族痴呆史、家族脑卒中史、合并高血压、合并高血脂、脑梗死位置和NIHSS评分对多发腔隙性脑梗死后血管性认知障碍的发生有显著影响,应在临床实践中加以重视,以制定有效的干预措施。Objective To investigate the independent risk factors for vascular cognitive impairment after multiple lacunar infarction.Methods By using regression analysis,the effects of age,education,marital status,ethnicity,smoking history,drinking history,exercise status,diet status,family history of dementia,family history of hypertension,family history of stroke,family history of diabetes,combined heart disease,combined hypertension,combined hyperlipidemia,combined diabetes,location of cerebral infarction and NIHSS score on vascular cognitive impairment after multiple lacunar infarction were studied.Results Among 450 patients in this study,40(8.89%)patients developed vascular cognitive impairment.Age,marital status,exercise status,family history of dementia,family history of stroke,combined hypertension,combined hyperlipidemia,location of cerebral infarction and NIHSS score were independent risk factors for vascular cognitive impairment after multiple lacunar infarction(P<0.05).Conclusion Age,marital status,exercise status,family history of dementia,family history of stroke,combined hypertension,combined hyperlipidemia,location of cerebral infarction and NIHSS score have significant impact on the occurrence of vascular cognitive impairment after multiple lacunar infarction,and should be paid attention to in clinical practice to develop effective intervention measures.

关 键 词：多发腔隙性脑梗死 血管性认知障碍 风险因素 回归分析 

分 类 号：R743.33[医药卫生—神经病学与精神病学]