不同脂质成分影响认知障碍的研究进展  

Research progress on the effects of different lipid components on cognitive impairment

作　　者：靳宇飞 王蕾[1] JIN Yufei;WANG Lei(Third Hospital of Shanxi Medical University/Shanxi Bethune Hospital/Shanxi Academy of Medical Sciences/Tongji Shanxi Hospital,Taiyuan 030032,China)

机构地区：[1]山西医科大学第三医院(山西白求恩医院山西医学科学院同济山西医院),山西太原030032

出　　处：《中国实用神经疾病杂志》2024年第6期784-788,共5页Chinese Journal of Practical Nervous Diseases

基　　金：山西省基础研究计划自然科学研究面上项目(编号:202203021211068)。

摘　　要：认知障碍是目前主要公共卫生挑战之一,其发病机制尚不明确。目前针对认知障碍尚未发现有效的治疗及干预措施,大部分研究表明通过干预血管危险因素可预防或减缓认知衰退,其中脂质组学成为研究热点。脂质是人体的重要组成部分,其成分可通过不同途径影响认知功能。因此,本文就脂质中常见成分对认知功能的影响做一综述。Cognitive impairment is one of the major public health challenges,and its pathogenesis remains unclear.At present,no effective treatment and intervention measures have been found for cognitive impairment.Most studies have shown that cognitive decline can be prevented or slowed down by intervening vascular risk factors,among which lipidomics has become a research hotspot.Lipids are an important part of the human body,and their composition can affect cognitive function in different ways.Therefore,this article reviews the effects of common lipid components on cognitive function.

关 键 词：脂质 认知障碍 脂肪酸 甘油脂 甘油磷脂 鞘脂 甾醇 

分 类 号：R743[医药卫生—神经病学与精神病学]