复方刺五加散对母猪和哺乳仔猪血清生化、抗氧化和免疫指标的影响  

Effects of Compound Acanthopanax senticosus Powder on Serum Biochemical,Antioxidant and Immune Indexes of Sows and Suckling Piglets

作　　者：彭雄 李想 伍蓉蓉 曹宇航 刘自逵[1,2] 柳高峰 孙志良 伍勇[1] PENG Xiong;LI Xiang;WU Rongrong;CAO Yuhang;LIU Zikui;LIU Gaofeng;SUN Zhiliang;WU Yong(College of Veterinary Medicine,Hunan Agricultural University,Changsha 410128,China;Hunan Canzoho Biological Technology Co.,Ltd.,Liuyang 410329,China)

机构地区：[1]湖南农业大学动物医学院,长沙410128 [2]湖南加农正和生物技术有限公司,浏阳410329

出　　处：《动物营养学报》2024年第5期2911-2923,共13页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：湖南省普通高校青年骨干教师资助项目(2020⁃43)。

摘　　要：本试验旨在研究妊娠后期和哺乳期母猪饲喂复方刺五加散对母猪和哺乳仔猪血清生化、抗氧化和免疫指标的影响。试验选取60头胎次、配种时间和体况相近的健康长×大二元母猪,随机分为4组,每组15个重复,每个重复1头母猪。对照组、低剂量组、中剂量组和高剂量组母猪分别饲喂在基础饲粮中添加0、0.5、1.0和2.0 kg/t复方刺五加散的试验饲粮,饲喂试验从母猪妊娠第80天开始至哺乳第21天结束。结果显示:1)与对照组相比,中剂量组、高剂量组哺乳仔猪的平均日增重有增加的趋势(P=0.091)。2)在哺乳第1天,与对照组相比,低剂量组母猪血清白蛋白(ALB)、无机磷(IP)含量显著升高(P<0.05),血清葡萄糖(GLU)含量显著降低(P<0.05);在哺乳第21天,与高剂量组相比,对照组、低剂量组和中剂量组母猪血清天门冬氨酸氨基转移酶(AST)活性显著升高(P<0.05);与对照组相比,低剂量组21日龄哺乳仔猪血清甘油三酯(TG)含量显著升高(P<0.05)。3)在哺乳第1天,与对照组相比,各剂量组母猪血清超氧化物歧化酶(SOD)活性显著升高(P<0.05),同时血清丙二醛(MDA)含量显著降低(P<0.05);在哺乳第21天,与对照组相比,低剂量组、中剂量组母猪血清过氧化氢酶(CAT)活性显著升高(P<0.05),高剂量组母猪血清总抗氧化能力(T-AOC)显著降低(P<0.05),低剂量组、中剂量组母猪血清MDA含量有降低趋势(P=0.075);低剂量组21日龄哺乳仔猪血清T-AOC显著高于对照组、中剂量组和高剂量组(P<0.05),低剂量组、中剂量组血清MDA含量较对照组有降低趋势(P=0.081)。4)与对照组相比,低剂量组哺乳第1、21天母猪血清白细胞介素-1β(IL-1β)、白细胞介素-6(IL-6)含量以及21日龄哺乳仔猪血清干扰素-γ(IFN-γ)、白细胞介素-2(IL-2)和IL-6含量显著降低(P<0.05);中剂量组哺乳第1天母猪血清IL-1β、IL-6含量与哺乳第21天母猪血清IFN-γ、IL-1β含量以及21日龄哺乳仔猪血清IFThe aim of this study was to investigate the effects of feeding compound Acanthopanax senticosus powder during late pregnancy and lactation on the serum biochemical,antioxidant and immune indexes of sows and sucking piglets.Sixty healthy Landrace×Yorkshire crossbred sows with similar parity,mating time and body condition were randomly divided into four groups(control group,low dose group,medium dose group and high dose group)and fed experimental diets supplemented with 0,0.5,1.0 and 2.0 kg/t compound Acan⁃thopanax senticosus powder based on as basal diet,respectively,with 15 replicates per group and one sow per replicate.The experiment began on day 80 of gestation and ended on day 21 of lactation.The results showed as follow:1)compared with the control group,the average daily gain of suckling piglets in the middle and high dose groups showed an increasing trend(P=0.091).2)On the 1st day of lactation,serum albumin(ALB)and inorganic phosphorus(IP)contents of sows in the low dose group was significantly increased(P<0.05),and serum glucose(GLU)content was significantly decreased compared with the control group(P<0.05);on the 21st day of lactation,serum aspartate aminotransferase(AST)activity of sows in the control group,low and medium dose groups was significantly increased compared with the high dose group(P<0.05);serum tri⁃glyceride(TG)content of 21⁃day⁃old suckling piglets in the low dose group was significantly increased com⁃pared with the control group,(P<0.05).3)On the 1st day of lactation,compared with the control group,se⁃rum superoxide dismutase(SOD)activity of sows in each dose group was significantly increased(P<0.05),while serum malondialdehyde(MDA)content was significantly decreased(P<0.05);on the 21st day of lac⁃tation,compared with the control group,serum catalase(CAT)activity of sows in low and medium dose groups was significantly increased(P<0.05),serum total antioxidant capacity(T⁃AOC)of sows in high dose group were significantly decreased(P<0.05),and serum MDA content of sows in lo

关 键 词：复方刺五加散 母猪 哺乳仔猪 抗氧化能力 免疫指标 

分 类 号：S816[农业科学—饲料科学]