饲粮添加不同形态锌对肉仔鸡血浆生化指标、抗氧化能力及免疫功能的影响  

Effects of Dietary Different Forms of Zinc on Plasma Biochemical Indices,Antioxidant Capacity and Immune Function of Broilers

作　　者：薛萌晓 王传龙 张卫云 张丽阳[2] 崔小燕 李婷婷[1] 胡云 罗绪刚 XUE Mengxiao;WANG Chuanlong;ZHANG Weiyun;ZHANG Liyang;CUI Xiaoyan;LI Tingting;HU Yun;LUO Xugang(Poultry Mineral Nutrition Laboratory,College of Animal Science and Technology,Yangzhou University,Yangzhou 225009,China;Mineral Nutrition Research Division,Institute of Animal Science,Chinese Academy of Agricultural Science,Beijing 100193,China)

机构地区：[1]扬州大学动物科学与技术学院,家禽矿物元素营养实验室,扬州225009 [2]中国农业科学院北京畜牧兽医研究所,矿物元素营养研究室,北京100193

出　　处：《动物营养学报》2024年第5期2982-2991,共10页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：国家自然科学基金面上项目(31972583);国家自然科学基金重点国际(地区)合作研究项目(32120103011);江苏省双创人才项目(JSSCRC2021541);江苏省双创团队项目(JSSCTD202147)。

摘　　要：本试验旨在研究饲粮添加不同形态锌[无机硫酸锌(ZnSO4)和中等螯合强度蛋白锌(Zn-Prot M)]对肉仔鸡血浆生化指标、抗氧化能力及免疫功能的影响。试验选用300只1日龄爱拔益加肉仔鸡公雏,1~13日龄统一饲喂不添加锌的半纯合饲粮,于14日龄从中选取体重接近的240只鸡,采用单因子完全随机试验设计,随机分成3组,每组8个重复,每个重复10只鸡。对照组饲喂不添加锌的基础饲粮,试验组分别饲喂基础饲粮中添加60 mg/kg ZnSO_(4)和Zn-Prot M(以锌计)的试验饲粮。试验期26 d。结果表明:1)饲粮添加不同形态锌对血浆白蛋白、甘油三酯和高密度脂蛋白胆固醇含量以及谷丙转氨酶和谷草转氨酶活性均无显著影响(P>0.05)。与对照组相比,饲粮添加ZnSO_(4)和Zn-Prot M均显著降低了血浆中总胆固醇和低密度脂蛋白胆固醇含量(P<0.05);与ZnSO4组相比,饲粮添加Zn-Prot M显著提高了血浆中总蛋白和球蛋白含量(P<0.05),显著降低了血浆中低密度脂蛋白胆固醇含量和乳酸脱氢酶活性(P<0.05)。2)与对照组相比,饲粮添加ZnSO4和Zn-Prot M均显著提高了血浆中总超氧化物歧化酶和铜锌超氧化物歧化酶活性及总抗氧化能力(P<0.05),显著降低了血浆中丙二醛含量(P<0.05);与ZnSO4组相比,饲粮添加Zn-Prot M显著提高了血浆中总超氧化物歧化酶和铜锌超氧化物歧化酶活性(P<0.05),显著降低了血浆中丙二醛含量(P<0.05)。3)饲粮添加不同形态锌对血浆中白细胞介素-6、免疫球蛋白A和免疫球蛋白G含量无显著影响(P>0.05)。与对照组相比,饲粮添加ZnSO_(4)和Zn-Prot M均显著降低了血浆中白细胞介素-1β含量(P<0.05);与ZnSO_(4)组相比,饲粮添加Zn-Prot M显著降低了肉仔鸡血浆中白细胞介素-1β含量(P<0.05)。综上所述,饲粮添加ZnSO_(4)和Zn-Prot M显著影响了肉仔鸡血浆中总蛋白、球蛋白、总胆固醇和低密度脂蛋白胆固醇含量以及乳酸脱氢酶活性等生化指�This experiment was conducted to study the effects of dietary different forms of zinc[inorganic zinc sulfate(ZnSO_(4))and zinc proteinate with moderate chelation strength(Zn⁃Prot M)]on plasma biochemical indices,antioxidant capacity and immune function of broilers.A total of 300 one⁃day⁃old male Arbor Acres broilers were fed a semi⁃purified diet without zinc from 1 to 13 days of age.At 14 days of age,a total of 240 broilers with similar body weight were selected and randomly divided into 3 groups with 8 replicates per group and 10 broilers per replicate according a completely randomized design.Broilers in the control group were fed a basal diet without zinc,and others in experimental groups were fed basal diets supplemented with 60 mg/kg ZnSO_(4) and Zn⁃Prot M(as zinc),respectively.The experiment lasted for 26 days.The results showed as fol⁃lows:1)dietary different forms of zinc had no significant effects on the albumin,triglyceride and high⁃density lipoprotein cholesterol contents and aspartate transaminase(AST)and alanine aminotransferase(ALT)activi⁃ties in plasma(P>0.05).Compared with the control group,dietary ZnSO_(4) and Zn⁃Prot M significantly de⁃creased the contents of total cholesterol and low⁃density lipoprotein cholesterol in plasma(P<0.05);compared with the ZnSO_(4) group,dietary Zn⁃Prot M significantly increased the contents of total protein and globulin in plasma(P<0.05),and significantly decreased the low⁃density lipoprotein cholesterol content and lactate dehy⁃drogenase activity in plasma(P<0.05).2)Compared with the control group,dietary ZnSO_(4) and Zn⁃Prot M significantly increased the total superoxide dismutase and copper zinc superoxide dismutase activities and total antioxidant capacity in plasma(P<0.05),and significantly decreased the plasma malondialdehyde content(P<0.05);compared with the ZnSO_(4) group,dietary Zn⁃Prot M significantly increased the activities of total superoxide dismutase and copper zinc superoxide dismutase in plasma(P<0.05),and significantl

关 键 词：锌源 肉仔鸡 血浆生化指标 抗氧化功能 免疫功能 

分 类 号：S831[农业科学—畜牧学]