淀粉样蛋白PET脑成像在阿尔茨海默病诊疗中的价值  

Crucial Role ofβ-Amyloid PET in the Diagnosis and Therapeutic Evaluation of Alzheimer's Disease

作　　者：卢洁[1] LU Jie(Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University,Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Key Laboratory of Neurodegenerative Diseases,Ministry of Education,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院放射与核医学科,磁共振成像脑信息学北京市重点实验室,神经变性病教育部重点实验室,北京100053

出　　处：《中国医学影像学杂志》2024年第5期417-419,425,共4页Chinese Journal of Medical Imaging

基　　金：北京市教育科学“十三五”规划项目(CHDB2020174)

摘　　要：阿尔茨海默病是最常见的神经退行性疾病,我国患病人数居全球首位,严重危害老年人健康,家庭照护和社会经济负担巨大。β-淀粉样蛋白PET脑成像技术可在分子水平无创、精准评估阿尔茨海默病患者脑内β-淀粉样蛋白沉积情况,是早期精准诊断及疗效评估的重要方法。Alzheimer's disease,the most prevalent neurodegenerative disease,with China having the highest number of cases globally,is an important public health problem because of its heavy family,economic,and social burden.β-amyloid PET imaging can be used to noninvasively and accurately evaluate the changes ofβ-amyloid deposition in the brain at the molecular level in Alzheimer's disease,which is a crucial imaging tool for early diagnosis and intervention evaluation.

关 键 词：阿尔茨海默病 正电子发射断层摄影术 Β-淀粉样蛋白 诊断 治疗结果 

分 类 号：R749.16[医药卫生—神经病学与精神病学] R445.5[医药卫生—临床医学]