高帧率超声造影在肝局灶性病变中的诊断价值  

Diagnosis of High Frame Rate Contrast-Enhanced Ultrasound in Focal Liver Lesions

作　　者：张雪菡 周青[2] 周乔丹 陈琴[2] ZHANG Xuehan;ZHOU Qing;ZHOU Qiaodan;CHEN Qin(Department of Ultrasound,Sichuan Academy of Medical Science&Sichuan Provincial People's Hospital,Chengdu 610072,China;不详)

机构地区：[1]遵义医科大学,贵州遵义563000 [2]四川省医学科学院·四川省人民医院超声科,四川成都610072

出　　处：《中国医学影像学杂志》2024年第5期473-478,共6页Chinese Journal of Medical Imaging

摘　　要：目的探讨高帧率超声造影(H-CEUS)在肝脏局灶性病变(FLLs)定性诊断中的应用价值。资料与方法回顾性收集2021年8月—2022年8月四川省人民医院的72例FLLs。所有患者均先行常规超声发现病灶,后行超声造影(CEUS)及H-CEUS,对比两种方法显示的开始增强时间、增强方向、血管形态、峰值强度、增强均匀度等,评估CEUS、H-CEUS对FLLs的诊断价值。结果相较于CEUS,H-CEUS能够更清楚地显示FLLs动脉期增强方向、血管形态及增强后均匀度。CEUS、H-CEUS诊断FLLs的敏感度、特异度、准确度、阳性预测值、阴性预测值、曲线下面积分别为87.10%、96.77%,85.37%、87.80%,86.11%、91.67%,81.82%、85.71%,89.74%、97.30%,0.862、0.923。结论相较于CEUS,H-CEUS能够更清楚地显示病灶动脉期特征性表现,为FLLs的诊断提供了更丰富、可靠的信息,对FLLs具有较高的诊断效能。Purpose To investigate the value of high frame rate contrast-enhanced ultrasound(H-CEUS)in the qualitative diagnosis of focal liver lesions(FLLs).Materials and Methods Seventy-two patients with FLLs who visited Sichuan Provincial People's Hospital from August 2021 to August 2022 were retrospectively enrolled in this study.All patients were diagnosed by conventional ultrasound,followed by contrast-enhanced ultrasound(CEUS)and H-CEUS.The diagnostic value of CEUS and H-CEUS in FLLs was evaluated by comparing the initial enhancement time,enhancement direction,vascular morphology,peak intensity and enhancement uniformity displayed by the two methods.Results Compared with CEUS,H-CEUS could more clearly show the direction of arterial phase enhancement,vascular morphology and uniformity after enhancement of the lesion.The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of CEUS and H-CEUS for the diagnosis of 72 FLLs were 87.10%,96.77%;85.37%,87.80%;86.11%,91.67%;81.82%,85.71%and 89.74%,97.30%,respectively.The area under the curve of CEUS and H-CEUS for the diagnosis of FLLs was 0.862 and 0.923,respectively.Conclusion Compared with CEUS,H-CEUS can more clearly show the characteristic manifestations of the arterial phase of lesions,providing richer and more reliable information for the qualitative diagnosis of FLLs.H-CEUS has a high diagnostic efficacy for FLLs.

关 键 词：肝疾病 肝肿瘤 超声检查 造影剂 

分 类 号：R735.7[医药卫生—肿瘤] R445.1[医药卫生—临床医学]