脑卒中相关性肺炎患者肺部多药耐药菌感染的影响因素  

Influencing Factors of Pulmonary Multidrug Resistant Bacteria Infection in Patients with Stroke-associated Pneumonia

作　　者：武丽丽[1] 赵阳 曹凌云[1] Wu Lili;Zhao Yang;Cao Lingyun(Department of Third Internal Medicine,Weifang People's Hospital,Weifang 261041,Shandong Province,China)

机构地区：[1]潍坊市人民医院神经内三科,山东潍坊261041

出　　处：《中外医药研究》2024年第11期139-141,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:分析脑卒中相关性肺炎患者肺部多药耐药菌感染的影响因素。方法:采用便利抽样的方法,回顾性分析2017年1月—2022年12月潍坊市人民医院接受治疗的168例脑卒中相关性肺炎患者的临床资料,包括性别、年龄、脑卒中类型、意识障碍情况、吞咽功能情况、合并糖尿病、合并高血压、肺部感染分型、预防性使用抗生素情况、胃管留置情况等,分析脑卒中相关性肺炎患者肺部多药耐药菌感染的独立影响因素。结果:168例脑卒中相关性肺炎患者中,有113例(67.26%)为脑卒中后肺部多药耐药菌感染。单因素分析结果显示,多药耐药菌感染组意识障碍、晚发型肺炎、预防性使用抗生素占比高于非多药耐药菌感染组,差异有统计学意义(P<0.001)。Logistic多因素分析结果显示,意识障碍、晚发型肺炎、预防性使用抗生素是脑卒中后肺部多药耐药菌感染的独立影响因素(P<0.05)。结论:意识障碍、晚发型肺炎、预防性使用抗生素是脑卒中后肺部多药耐药菌感染的独立影响因素。Objective:To analyze the influencing factors of pulmonary multidrug resistant bacteria infection in patients with stroke-associated pneumonia.Methods:The clinical data of 168 patients with stroke-associated pneumonia treated in Weifang People's Hospital from January 2017 to December 2022 were retrospectively analyzed by convenient sampling method.It included gender,age,stroke type,disorder of consciousness,swallowing function,diabetes mellitus,hypertension,pulmonary infection type,preventive antibiotic use,gastric tube indentation,etc.The independent influencing factors of pulmonary multidrug resistant bacteria infection in patients with stroke-associated pneumonia were analyzed.Results:Among 168 patients with stroke-associated pneumonia,113(67.26%)were multidrug resistant pulmonary infection after stroke.The results of single factor analysis showed that the proportion of consciousness disorder,late-onset pneumonia and prophylactic antibiotic use in multidrug resistant pulmonary infection group was higher than that in non-multidrug resistant pulmonary infection group,and the difference was statistically significant(P<0.001).Logistic multivariate analysis showed that consciousness disturbance,late-onset pneumonia and prophylactic use of antibiotics were independent influencing factors of multidrug resistant pulmonary infection after stroke(P<0.05).Conclusion:Disturbance of consciousness,late-onset pneumonia and prophylactic use of antibiotics are independent influencing factors of multidrug resistant pulmonary infection after stroke.

关 键 词：脑卒中相关性肺炎 耐药菌感染 意识障碍 抗生素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]