基于倾向性评分匹配法探讨急性脑梗死并发血管性痴呆的影响因素及预防建议  

Exploration of influencing factors and preventive suggestions of acute cerebral infarction complicated with vascular dementia based on propensity score matching method

作　　者：朱莎莎[1] Zhu Shasha(Department of Neurology,the Sixth People's Hospital of Anyang City,Anyang,Henan 455000,China)

机构地区：[1]安阳市第六人民医院神经内科,河南安阳455000

出　　处：《齐齐哈尔医学院学报》2024年第10期940-946,共7页Journal of Qiqihar Medical University

摘　　要：目的 基于倾向性评分匹配法(PSM)探讨急性脑梗死(ACI)并发血管性痴呆(VD)的影响因素,并针对性提出预防建议措施。方法 选择2019年1月—2023年1月本院收治的258例ACI患者作为研究对象,按有无发生VD分为VD组和无VD组两组,匹配前,VD组54例无VD组204例;匹配后,VD组52例无VD组52例。比较匹配前后两组一般资料;基于PSM匹配两组资料,采用Logistic回归模型分析匹配后ACI并发VD的影响因素。结果 258例患者中54例发生VD,VD发生率为20.93%;匹配前,VD组患者受教育年限短于无VD组,差异有统计学意义(P<0.05);VD组患者高血压、高脂血症、糖尿病、脑梗死病史、额叶脑梗死、脑白质疏松构成比及入院时NIHSS评分高于无VD组,差异有统计学意义(P<0.05);VD组患者脑梗死面积大于无VD组,差异有统计学意义(P<0.05);VD组患者ACI发病至入院时间长于VD组,差异有统计学意义(P<0.05);VD组患者出院后康复治疗构成比低于无VD组,差异有统计学意义(P<0.05);匹配后,VD组患者受教育年限短于无VD组,差异有统计学意义(P<0.05);VD组患者高血压、额叶脑梗死构成比及入院时NIHSS评分高于无VD组,差异有统计学意义(P<0.05);VD组患者脑梗死面积大于无VD组,差异有统计学意义(P<0.05);VD组患者ACI发病至入院时间长于无VD组,差异有统计学意义(P<0.05);VD组患者出院后康复治疗构成比低于无VD组,差异有统计学意义(P<0.05);Logistic回归模型分析显示受教育年限、高血压、额叶脑梗死、脑梗死面积、出院后康复治疗是ACI并发VD的影响因素(P<0.05)。结论 基于PSM法发现受教育年限、高血压、额叶脑梗死、脑梗死面积、出院后康复治疗是ACI并发VD的影响因素。Objective To explore the influencing factors of acute cerebral infarction(ACI)complicated with vascular dementia(VD)based on propensity score matching(PSM)method,and to propose targeted preventive measures.Methods A total of 258 patients suffering from ACI who were admitted to our hospital from January 2019 to January 2023 were enrolled as study subjects.According to the occurrence of VD,they were divided into the VD group and the non-VD group.Before matching,there were 54 cases in the VD group and 204 cases in the non-VD group;After matching,there were 52 patients in the VD group and 52 patients in the non-VD group.The general data of the two groups before and after matching were compared.Based on PSM,the data of the two groups were matched,and the Logistic regression model was used to analyze the influencing factors of ACI complicated with VD after matching.Results 54 of the 258 patients suffered from VD,and the incidence rate of VD was 20.93%.Before matching,the years of education in the VD group was shorter than that in the non-VD group,and the difference was statistically significant(P<0.05).The proportions of hypertension,hyperlipidemia,diabetes,history of cerebral infarction,and cerebral white matter rarefaction and NIHSS score of admission in the VD group were higher than those of the non-VD group(P<0.05).The cerebral infarction area in the VD group was larger than that in the non-VD group,and the difference was statistically significant(P<0.05).The time since ACI onset to admission in the VD group was longer than that of the non-VD group(P<0.05).After matching,the years of education in the VD group was shorter than that in the non-VD group,and the difference was statistically significant(P<0.05).The proportion of hypertension,frontal lobe cerebral infarction and NIHSS score on admission in the VD group were higher than those in the non-VD group,and the differences were statistically significant(P<0.05).The cerebral infarction area in the VD group was larger than that in the non-VD group,and the differenc

关 键 词：急性脑梗死 血管性痴呆 影响因素 倾向性评分匹配法 

分 类 号：R743.3[医药卫生—神经病学与精神病学]