EGRIS评分联合CONUT评分对GBS患者需要机械通气的预测价值  

Predictive value of EGRIS score combined with CONUT score for the need of mechanical ventilation in Guillain-Barrésyndrome

作　　者：张威 姚倩 屈小莹 王钰乔 张卫 杨新新 ZHANG Wei;YAO Qian;QU Xiaoying;WANG Yuqiao;ZHANG Wei;YANG Xinxin(The Fist Clinical College,Xuzhou Medical University,Xuzhou,Jiangsu 221002,China;Department of Neurology,Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu 221002,China)

机构地区：[1]徐州医科大学第一临床医学院,江苏徐州221002 [2]徐州医科大学附属医院神经内科,江苏徐州221002

出　　处：《热带医学杂志》2024年第4期590-595,共6页Journal of Tropical Medicine

基　　金：国家自然科学基金(81671269)。

摘　　要：目的探讨Erasmus GBS呼吸功能不全评分(EGRIS)、营养控制状况(CONUT)评分对吉兰-巴雷综合征(GBS)患者需要机械通气的预测价值,为临床早期识别高危患者并及时干预提供依据。方法选取2014年12月-2023年8月期间徐州医科大学附属医院收治的192例GBS患者,根据是否需要行机械通气将患者分为机械通气组(n=27)和非机械通气组(n=165)。比较两组患者一般资料及EGRIS评分、CONUT评分,运用多因素logistic回归分析探究可能影响GBS患者机械通气的危险因素;使用受试者工作特征(ROC)曲线评价EGRIS评分及CONUT评分对GBS患者需要机械通气的预测价值。结果与非机械通气组相比,机械通气组EGRIS评分及CONUT评分均更高,差异有统计学意义(Z=-6.035、-5.778,P均<0.001)。多因素logistic回归分析结果显示,EGRIS评分与CONUT评分均为GBS患者需要机械通气的危险因素(P<0.05)。ROC曲线显示,EGRIS评分、CONUT评分及两者联合预测GBS患者需要机械通气的曲线下面积分别为0.856、0.841、0.909,灵敏度分别为88.89%、70.37%、77.78%,特异性分别为67.88%、87.88%、86.06%。结论EGRIS评分、CONUT评分对GBS机械通气风险均具有一定的预测价值,两者联合比单独指标具有更好的预测价值。Objective The study aimed to investigate the predictive value of Erasmus GBS respiratory insufficiency score(EGRIS)and controlling nutritional status(CONUT)score for the need of mechanical ventilation in patients with GuillainBarre syndrome(GBS).Methods A total of 192 patients with GBS admitted to the Affiliated Hospital of Xuzhou Medical University from December 2014 to August 2023 were selected,According to whether mechanical ventilation,they were divided into mechanical ventilation group and non-mechanical ventilation group.The general data and EGRIS score,CONUT score were compared between the two groups.Multivariate logistic regression analysis was used to analyze the risk factors of mechanical ventilation.Receiver operator characteristic(ROC)curve was used to analyze the predictive value of EGRIS score and CONUT score on mechanical ventilation.Results The levels of EGRIS score and CONUT score in mechanical ventilation group were higher than those in non-mechanical ventilation group,the differences were statistically significant(Z=-6.035,-5.778;all P<0.001).Multivariate logistic regression analysis showed EGRIS score and CONUT score were the independent risk factors for the need of mechanical ventilation(P<0.05).The ROC curve showed that the area under the curve of EGRIS score,CONUT score and the combination of the two were 0.856,0.841 and 0.909,respectively;the sensitivities were 88.89%,70.37%and 77.78%,respectively,and the specificities were 67.88%,87.88%and 86.06%,respectively.Conclusion Both EGRIS score and CONUT score had certain predictive value for mechanical ventilation in patients with GBS,but the combination of them was more reliable in the prediction of the risk of mechanical ventilation in patients with GBS.

关 键 词：吉兰-巴雷综合征 Erasmus GBS呼吸功能不全评分 营养控制状况评分 机械通气 

分 类 号：R745[医药卫生—神经病学与精神病学]