放射治疗患者胸大肌前假体乳房再造的研究进展  

Advances of prepectoral breast reconstruction in patients received radiotherapy

作　　者：马小睦 刘春军 Ma Xiaomu;Liu Chunjun(Department of Breast Comprehensive Plastic Surgery,Plastic Surgery Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100144,China)

机构地区：[1]中国医学科学院北京协和医学院整形外科医院乳腺综合整形科,北京100144

出　　处：《中华整形外科杂志》2024年第4期455-460,共6页Chinese Journal of Plastic Surgery

基　　金：国家临床重点专科建设项目(21048)。

摘　　要：近年来,随着脂肪移植和补片技术的发展,胸大肌前假体乳房再造(PBR)重新进入了医生视野,并迅速成为研究热点。已有多项meta分析表明,PBR与胸大肌后平面再造在安全性上无差异,且具有疼痛轻、无动态畸形等诸多优势。放射治疗(简称放疗)是乳腺癌的常规治疗手段,需放疗的乳腺癌患者比例高达40%,但目前该人群接受PBR的安全性和有效性尚无定论。该文回顾了针对放疗患者行PBR手术的临床研究,从放疗对软组织和置入物的影响、乳腺癌切除术后放疗人群PBR的适应证与禁忌证、放疗人群PBR的研究现状、脂肪移植对放疗患者PBR的影响、目前研究的局限性5个方面进行综述,为PBR的临床应用和未来研究提供参考和方向。In recent years,with the development of autologous fat grafting and the use of scaffolds,prepectoral breast reconstruction(PBR)has regained popularity and ignited a heated discussion.Several meta-analyses have shown that PBR is safe when compared with subpectoral breast reconstruction,the standard of prosthetic breast reconstruction.There are many advantages in PBR such as mild pain and no dynamic deformity.Radiotherapy,required by up to 40%of patients,is a routine treatment for breast cancer.However,the safety and efficacy of PBR in this population remain inconclusive.Therefore,we reviewed clinical researches concerning PBR in patients who received radiotherapy,with the purpose to provide reference for clinical application and future study of PBR.We analysed the following five aspects:the influence of radiation on soft tissue and the implant,indications and contraindications,the research status of PBR in patients with radiotherapy,the influence of fat grafting on PBR in patients with radiotherapy and the limitation of the present study.

关 键 词：乳房成形术 胸大肌前假体乳房再造 放射治疗 安全性 有效性 

分 类 号：R730.55[医药卫生—肿瘤] R737.9[医药卫生—临床医学]