超声造影联合肿瘤自身抗体检测对早期肺癌的诊断价值  

The Diagnostic Value of Contrast-Enhanced Ultrasound Combined with Tumor Autoantibody Detection for Early Lung Cancer

作　　者：周美君[1] 王健 肖雅丽[1] 唐琼 谭卫龙 ZHOU Mei-jun;WANG Jian;XIAO Ya-li;TANG Qiong;TAN Wei-long(Affiliated Hospital of Xiangnan University,Hunan Chenzhou 423000)

机构地区：[1]湘南学院附属医院,湖南郴州423000

出　　处：《中国医疗器械信息》2024年第10期33-35,共3页China Medical Device Information

基　　金：湖南省郴州市科技创新能力培育计划项目(项目名称:超声造影定量分析联合7项肿瘤自身抗体检测对早期肺癌的诊断研究,项目编号:lcyl2021106)。

摘　　要：目的:研讨超声造影定量分析联合7项肿瘤自身抗体检测对早期肺癌的诊断价值。方法:收集本院自2021年10月~2023年10月60例早期肺癌患者为研究对象,以病理诊断为金标准,分析超声造影定量分析、7项肿瘤自身抗体检测、超声造影定量分析联合7项肿瘤自身抗体检测诊断价值。结果:以病理结果为金标准,超声造影定量分析和7项肿瘤自身抗体检测与病理结果之间均有显著差异。联合检测诊断优于超声造影定量分析和7项肿瘤自身抗体检测,更符合金标准;联合应用诊断的敏感度和准确性均显著高于超声造影定量分析和7项肿瘤自身抗体检测,指标对比明显,P<0.01;联合诊断截断值、敏感性最高,特异性最低,曲线下面积最高,与超声造影定量分析和7项肿瘤自身抗体检测有显著差异,P<0.05。结论:超声造影定量分析联合7项肿瘤自身抗体检测用于肺癌的早期诊断具有临床应用价值。Objective:To explore the diagnostic value of contrast-enhanced ultrasound quantitative analysis combined with 7 tumor autoantibody tests for early lung cancer.Methods:A total of 60 early-stage lung cancer patients in our hospital from October 2021 to October 2023 were collected as research subjects.Pathological diagnosis was used as the gold standard,and the diagnostic values of ultrasound contrast quantitative analysis,7 tumor autoantibody tests,ultrasound contrast quantitative analysis combined with 7 tumor autoantibody tests were analyzed.Results:Using pathological results as the gold standard,there were significant differences between the quantitative analysis of contrast-enhanced ultrasound and the detection of 7 tumor autoantibodies and pathological results.Joint detection diagnosis is superior to quantitative analysis of contrast-enhanced ultrasound and detection of 7 tumor autoantibodies,and more in line with alloy standards;The sensitivity and accuracy of combined application diagnosis are significantly higher than those of contrast-enhanced ultrasound quantitative analysis and 7 tumor autoantibody tests,with a significant difference in indicators(P<0.01).The cutoff value and sensitivity of combined diagnosis are the highest,with the lowest specificity and the highest area under the curve,which is significantly different from contrast-enhanced ultrasound quantitative analysis and 7 tumor autoantibody tests(P<0.05).Conclusion:The combination of contrast-enhanced ultrasound quantitative analysis and 7 tumor autoantibody tests has clinical application value for the early diagnosis of lung cancer.

关 键 词：超声造影 定量分析 肿瘤自身抗体 联合诊断 早期肺癌 

分 类 号：R734.2[医药卫生—肿瘤]