利用亲水作用色谱-质谱联用技术检测贝类毒素研究进展  

Progresses in detecting shellfish toxins with hydrophilic interaction chromatography-mass spectrometry

作　　者：郑旭颖 孙晓杰[1,3] 李兆新 邢丽红[1,3] 蒋万枫 ZHENG Xuying;SUN Xiaojie;LI Zhaoxin;XING Lihong;JIANG Wanfeng(Yellow Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Qingdao 266071,China;College of Food Science and Technology,Shanghai Ocean University,Shanghai 201306,China;Laboratory of Quality and Safety Risk Assessment for Aquatic Products(Qingdao)of Ministry of Agriculture and Rural Affairs,Qingdao 266071,China;Qingdao Institute for Food and Drug Control,Qingdao 266073,China)

机构地区：[1]中国水产科学研究院黄海水产研究所,山东青岛266071 [2]上海海洋大学食品学院,上海201306 [3]农业农村部水产品质量安全风险评估实验室(青岛),山东青岛266071 [4]青岛市食品药品检验研究院,山东青岛266073

出　　处：《海洋湖沼通报》2024年第2期186-191,共6页Transactions of Oceanology and Limnology

基　　金：国家重点研发计划“蓝色粮仓科技创新重点专项”(2019YFD0901700)。

摘　　要：贝类毒素是由海洋中有毒藻类产生的有毒高分子化合物,贝类通过摄食有毒藻类在体内蓄积,严重威胁消费者健康。本文综述了贝类毒素的分类及亲水作用色谱(HILIC)的保留机理和特点。重点介绍了亲水作用色谱-质谱联用(HILIC-MS)技术在贝类毒素测定方面的应用研究进展,并提出了HILIC-MS在贝类毒素检测分析方面的发展趋势。Shellfish toxins are toxic macromolecular compounds produced by toxic algae in the ocean.Shellfish accumulate in their body by ingesting toxic algae,which seriously threatens the health of consumers.In this paper,we reviewed the classification of shellfish toxins and the retention mechanism and characteristics of hydrophilic interaction chromatography(HILIC).The application of hydrophilic interaction chromatography-mass spectrometry(HILIC-MS)in determining shellfish toxins was introduced,and the development trend of HILIC-MS in the detection and analysis of shellfish toxins was put forward.

关 键 词：贝类毒素 亲水作用色谱-质谱联用(HILIC-MS) 检测 

分 类 号：TS254.7[轻工技术与工程—水产品加工及贮藏工程]