基于CiteSpace的功能性磁共振成像技术在阿尔茨海默病应用领域中的研究态势分析  

Research hotspots and frontiers of functional magnetic resonance imaging technology in the application field of Alzheimer’s disease based on CiteSpace

作　　者：赵志军 刘佳霖[1,2] 马建岭 张帆[2] 姜俊辰 ZHAO Zhijun;LIU Jialin;MA Jianling(Qinhuangdao Hospital,Dongfang Hospital,Beijing University of Chinese Medicine(Qinhuangdao Hospital of Traditional Chinese Medicine),Qinhuangdao 066000,China)

机构地区：[1]北京中医药大学东方医院秦皇岛医院(秦皇岛市中医医院),河北秦皇岛066000 [2]北京中医药大学东方医院

出　　处：《精神医学杂志》2024年第1期24-30,共7页Journal of Psychiatry

基　　金：北京中医药大学2020年度重点攻关项目(编号:2020-JYB-ZDGG-131)。

摘　　要：目的通过文献计量学方法探讨功能性磁共振成像(fMRI)在阿尔茨海默病(AD)应用领域中的研究现状与前沿热点,把握未来研究趋势,以期为今后的研究提供新的见解。方法采用CiteSpace软件系统对中国知网及Web of Science数据库建库至2023年11月检索到的关于fMRI在AD中应用的相关文献进行可视化分析。结果纳入中文文献共423篇,英文文献703篇,总体发文量呈上升趋势。共现、聚类分析可知研究热点多与“功能连接、低频振幅、认知障碍、认知功能、mild cognitive impairment、resting-state fMRI”等相关。研究前沿多提示与“早期诊断、鉴别诊断、新兴技术”等相关。结论fMRI在AD应用领域中研究范围广泛,融合新兴技术为其未来发展的方向。Objective To explore the current status and frontier hotspots of functional magnetic resonance imaging(fMRI)in the application field of Alzheimer’s disease(AD)through bibliometric methods,in order to grasp future research trends and provide new insights for future studies.Methods A visual analysis was conducted on the literatures related to the application of fMRI in AD,retrieved from the China National Knowledge Infrastructure and Web of Science databases up to November 2023 through the CiteSpace software system.Results The overall trend of literatures,in both Chinese and English,from 2004 to 2023 showed an upward trajectory,with 423 Chinese literatures and 703 English ones.Co-occurrence and cluster analysis revealed that research hotspots were mainly related to“functional connectivity,low-frequency amplitude,cognitive impairment,cognitive functions,mild cognitive impairment,and resting-state fMRI”.The research frontier was often associated with“early diagnosis,differential diagnosis,and emerging technologies”.Conclusion fMRI technology is widely applied in the field of AD,with the integration of emerging technologies being the direction for its future development.

关 键 词：阿尔茨海默病 功能磁共振 可视化 CITESPACE 

分 类 号：R749.16[医药卫生—神经病学与精神病学]