颞下颌关节骨关节病治疗的研究进展  

Research progress in the treatment of temporomandibular joint osteoarthrosis

作　　者：郭惟静 张哲[1] 刘志明[1] GUO Wei-Jing;ZHANG Zhe;LIU Zhi-ming(Department of Stomatology,Renmin Hospital of Wuhan University,Wuhan 430000,China)

机构地区：[1]武汉大学人民医院口腔科,430000

出　　处：《中华老年口腔医学杂志》2024年第2期119-124,共6页Chinese Journal of Geriatric Dentistry

基　　金：湖北省卫健委项目(WJ2023M072)。

摘　　要：颞下颌关节骨关节病(temporomandibular joint osteoarthrosis,TMJOA)是颞下颌关节紊乱病分类体系中的一个重要亚型。TMJOA的主要病理特点是软骨逐渐退化、软骨下骨发生重塑以及滑膜组织出现慢性炎症,并能引起剧烈疼痛和功能障碍。TMJOA的治疗策略旨在缓解疼痛,恢复关节功能。目前,对于TMJOA的治疗,非手术方式是最常见的临床治疗手段。这些疗法在大部分情况下都能有效地缓解临床症状和体征。近年来,随着组织工程的不断发展,为临床治疗TMJOA提供了更多的思路,现就目前常用的TMJOA诊疗方法和基础研究进展予以综述。Temporomandibular joint osteoarthrosis(TMJOA)is an important subtype in the classification system of temporomandibular disorders.The main pathological features of TMJOA are progressive cartilage degradation,remodeling of the subcartilage bone,and chronic inflammation of synovial tissue,which can cause severe pain and dysfunction.TMJOA’s treatment strategy aims to relieve pain and restore joint function.At present,non-surgical approaches are the most common clinical treatment for TMJOA.For the most part,these treatments are effective in relieving clinical symptoms and signs.In recent years,with the development of tissue engineering,more ideas have been provided for the clinical treatment of TMJOA.This article reviews the commonly used diagnostic and treatment methods and basic research progress of TMJOA at present.

关 键 词：颞下颌关节骨关节病 透明质酸 组织工程 富血小板衍生物 

分 类 号：R782.6[医药卫生—口腔医学]