长程居家多导睡眠监测评估发作性睡病日间嗜睡的应用价值  

Value of long-term at-home polysomnography in assessing excessive daytime sleepiness in narcolepsy patients

作　　者：杨静[1] 贾丽景[1] 毛卓锋[1] 李鑫[1] 李建华[1] 杜风萍 李震中[1] YANG Jing;JIA Lijing;MAO Zhuofeng(Department of Neurology,the Second Hospital of Hebei Medical University,Hebei,Shijiazhuang 050000,China)

机构地区：[1]河北医科大学第二医院神经内科,石家庄市050000

出　　处：《河北医药》2024年第11期1686-1689,共4页Hebei Medical Journal

基　　金：河北医科大学第二医院科学研究基金(编号:2HC202107)。

摘　　要：目的探讨一种可以定量评估发作性睡病日间嗜睡严重程度的监测方法并验证其效果。方法收集2021至2022年在河北医科大学第二医院神经内科确诊的发作性睡病患者相关信息,整理患者记录的睡眠日志,所有患者均采用便携式多导睡眠记录仪进行长程居家多导睡眠监测,记录睡眠发作次数、发作时间及发作时长。结果发作性睡病患者三项睡眠量表评估分数均明显高于健康对照者,差异有统计学意义(P<0.05)。多导睡眠监测数据结果与睡眠日志在发作次数、发作时长方面结果一致。用药前后、停药后多导睡眠监测记录的发作次数均多于睡眠日志记录,多导睡眠监测记录的发作时长长于睡眠日志记录。结论长程居家多导睡眠监测可作为定量评估发作性睡病日间嗜睡的方法,评估发作性睡病病情严重程度及药物治疗的效果,提供更加客观的睡眠数据。Objective To explore a monitoring method that can quantitatively evaluate the severity of excessive daytime sleepiness in patients with narcolepsy and to verify its effect.Methods Clinical data of narcolepsy patients diagnosed in the Department of Neurology,the Second Hospital of Hebei Medical University from 2021 to 2022 were collected.TheiRrecordings of sleep logs were analyzed.All patients were monitored foRthe number,time and duration of sleep attacks using a long-term at-home portable polysomnography.Results The three sleep scale assessment scores of narcolepsy patients were significantly higheRthan those of healthy controls(P<0.05).The polysomnography data results were consistent with the sleep log recordings,including the numbeRand duration of sleep attacks.The numbeRof sleep attacks before and afteRmedications and afteRwithdrawal recorded by polysomnography was higheRthat of sleep log recordings,and the duration of sleep attacks recorded by the formeRmethod was longer.Conclusion Long-term at-home polysomnography can be used as a method to quantitatively evaluate daytime sleepiness,which can evaluate the severity and the effect of drug treatment,and provide more objective sleep data in patients with narcolepsy.

关 键 词：发作性睡病 日间嗜睡 多导睡眠监测 评估方式 效果 

分 类 号：R741[医药卫生—神经病学与精神病学]