基于深度学习的非零水平集保凸的左心室分割  

Left ventricle segmentation based on non-zero level set preserving convexity

作　　者：李季 胡锦萍 LI Ji;HU Jinping(School of Mathematics and Statistics,Chongqing Technology and Business University,Chongqing 400067,China;Chongqing Key Laboratory of Statistical Intelligent Computing and Monitoring,Chongqing Technology and Business University,Chongqing 400067;School of Information and Communication Engineering,University of Electronic Science and Technology of China,Chengdu,Sichuan 611731,China)

机构地区：[1]重庆工商大学数学与统计学院,重庆400067 [2]重庆工商大学统计智能计算与检测重庆市重点实验室,重庆400067 [3]电子科技大学信息与通信工程学院,四川成都611731

出　　处：《光电子．激光》2024年第6期596-603,共8页Journal of Optoelectronics·Laser

基　　金：国家自然科学基金青年项目(11901071);重庆市自然科学基金面上项目(cstc2019jcyj-msxmX2019);重庆市教委自然科学项目(KJQN202000816)资助项目。

摘　　要：采用距离正则化水平集演化(distance regularized level set evolution, DRLSE)模型对左心室(left ventricle, LV)进行分割会使其产生锯齿状,分割效果较差。为了解决左心室分割目前面临的问题,本文首先使用基于卷积神经网络(convolutional neural network, CNN)的心肌中心线检测算法,取代了水平集方法的人工初始化过程,其次提出了一种基于非零水平集保凸的左心室分割方法。将距离正则化水平集演化(distance regularized level set evolution, DRLSE)模型(水平集方法)、深度学习方法与新方法的平均度中心性进行比较发现,新方法在收缩末期(end-systole, ES)的平均DC(dice coefficient)值为0.93,高于其他方法;除此之外,新方法在舒张末期(end-diastole, ED)与ES阶段的平均豪斯多夫距离(Hausdorff distance,HD)分别为2.51、2.54,明显小于深度学习方法以及水平集方法。实验结果表明,新方法能够有效地提高分割精度。Segmentation of the left ventricle(LV)using the distance regularized level set evolution(DRLSE)model causes it to be jagged and poorly segmented.To solve these problems currently faced by LV segmentation,this paper firstly uses a convolutional neural network(CNN)-based myocardial center-line detection algorithm to replace the manual initialization process of the level set method,and secondly proposes a non-zero level set-based preserving convexity LV segmentation method.Comparing the mean degree centrality of the DRLSE(level set method),deep learning method and the new method,it is found that theDC(dice coefficient)of the new method at the end-systole(ES)is 0.93,which is higher than the other methods.In addition,the mean Hausdorff distance(HD)of the new method at the end-diastolic(ED)and ES phases are 2.51 and 2.54,respectively,which is significantly smaller than those of the deep learning method and the level set method.The experimental results show that the new method can effectively improve the segmentation accuracy.

关 键 词：左心室(LV)分割 非零水平集 曲率 保凸 卷积神经网络(CNN) 

分 类 号：TP391.4[自动化与计算机技术—计算机应用技术]