Secondary diabetes due to different etiologies:Four case reports  

作　　者：Wen-Rong Song Xiao-Hong Xu Jia Li Jia Yu Yan-Xiong Li 

机构地区：[1]Department of Endocrinology,Hanchuan People's Hospital,Xiaogan 431600,Hubei Province,China [2]Department of Pneumology,Hanchuan People's Hospital,Xiaogan 431600,Hubei Province,China [3]Department of Imaging,Hanchuan People's Hospital,Xiaogan 431600,Hubei Province,China

出　　处：《World Journal of Clinical Cases》2024年第16期2813-2821,共9页世界临床病例杂志

摘　　要：BACKGROUND As research on diabetes continues to advance,more complex classifications of this disease have emerged,revealing the existence of special types of diabetes,and many of these patients are prone to misdiagnosis and underdiagnosis,leading to treatment delays and increased health care costs.The purpose of this study was to identify four causes of secondary diabetes.CASE SUMMARY Secondary diabetes can be caused by various factors,some of which are often overlooked.These factors include genetic defects,autoimmune disorders,and diabetes induced by tumours.This paper describes four types of secondary diabetes caused by Williams–Beuren syndrome,Prader–Willi syndrome,pituitary adenoma,and IgG4-related diseases.These cases deviate significantly from the typical progression of the disease due to their low incidence and rarity,often leading to their neglect in clinical practice.In comparison to regular diabetes patients,the four individuals described here exhibited distinct characteristics.Standard hypoglycaemic treatments failed to effectively control the disease.Subsequently,a series of examinations and follow-up history confirmed the diagnosis and underlying cause of diabetes.Upon addressing the primary condition,such as excising a pituitary adenoma,providing glucocorticoid supplementation,and implementing symptomatic treatments,all patients experienced a considerable decrease in blood glucose levels,which were subsequently maintained within a stable range.Furthermore,other accompanying symptoms improved.CONCLUSION Rare diseases causing secondary diabetes are often not considered in the diag-nosis of diabetes.Therefore,it is crucial to conduct genetic tests,antibody detection and other appropriate diagnostic measures when necessary to facilitate early diagnosis and intervention through proactive and efficient management of the underlying condition,ultimately improving patient outcomes.

关 键 词：Secondary diabetes IgG4-associated diseases Williams–Beuren syndrome Pituitary adenoma Prader-Willi syndrome Genetic defects Case report 

分 类 号：R735.1[医药卫生—肿瘤]