Laparoscopic spleen-preserving total pancreatectomy for the treatment of low-grade malignant pancreatic tumors:Two case reports and review of literature  

作　　者：Meng-Qing Sun Xiao-Man Kang Xiao-Dong He Xian-Lin Han 

机构地区：[1]Department of General Surgery,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China

出　　处：《World Journal of Clinical Cases》2024年第17期3206-3213,共8页世界临床病例杂志

基　　金：Supported by National High Level Hospital Clinical Research Funding,No.2022-PUMCH-B-003;National Multidisciplinary Cooperative Diagnosis and Treatment Capacity Building Project for Major Diseases。

摘　　要：BACKGROUND Function-preserving pancreatectomy can improve the long-term quality of life of patients with benign or low-grade malignant tumors,such as intraductal papillary mucinous neoplasms(IPMNs)and mucinous cystic neoplasms.However,there is limited literature on laparoscopic spleen-preserving total pancreatectomy(LSpTP)due to technical difficulties.CASE SUMMARY Patient 1 was a 51-year-old male diagnosed with IPMN based on preoperative imaging,showing solid nodules in the pancreatic head and diffuse dilation of the main pancreatic duct with atrophy of the distal pancreas.We performed L-SpTP with preservation of the splenic vessels,and the postoperative pathology report revealed IPMN with invasive carcinoma.Patient 2 was a 60-year-old male with multiple cystic lesions in the pancreatic head and body.L-SpTP was performed,and intraoperatively,the splenic vein was injured and required ligation.Postoperative pathology revealed a mucinous cystic tumor of the pancreas with low-grade dysplasia.Both patients were discharged on postoperative day 7,and there were no major complications during the perioperative period.CONCLUSION We believe that L-SpTP is a safe and feasible treatment for low-grade malignant pancreatic tumors,but more case studies are needed to evaluate its safety,efficacy,and long-term outcomes.

关 键 词：Complete laparoscopic surgery Spleen-preserving total pancreatectomy Lowgrade malignant pancreatic tumors Function-preserving pancreatectomy Case report 

分 类 号：R735.9[医药卫生—肿瘤]