肝硬化逆转和再代偿:既有证据和未来展望  

Liver cirrhosis reversal and recompensation:Existing evidence and future prospects

作　　者：杜韬 于冰[2] 罗薇[3] Tao Du;Bing Yu;Wei Luo(Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Department of Gastroenterology,The Second Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China;Department of Gastroenterology,The First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]广西医科大学,广西壮族自治区南宁市530021 [2]广西医科大学第二附属医院消化内科,广西壮族自治区南宁市530021 [3]广西医科大学第一附属医院消化内科,广西壮族自治区南宁市530021

出　　处：《世界华人消化杂志》2024年第5期320-326,共7页World Chinese Journal of Digestology

摘　　要：作为慢性肝病研究的新兴概念,近年来,肝硬化逆转和再代偿得到了越来越多的证据支持.增加对肝硬化逆转和再代偿的认识,有助于进一步划分肝硬化的自然病程,为肝硬化机制的基础研究和临床管理提供指导.然而,对两者的定义、潜在机制和影响因素的研究尚处于早期阶段.本文强调了肝硬化组织学和功能上的可逆性,概述了肝硬化逆转和再代偿的可能机制和诊断标准,总结了现有的相关研究证据,并提出了该领域亟待解决的挑战.As novel concepts in the field of hepatology,liver cirrhosis reversal and recompensation have gained more supporting evidence in recent years.Increasing awareness of these topics may help researchers classify the natural history of liver cirrhosis and provide guidance for fundamental research and clinical management.However,the research investigating the definition,mechanisms,and influencing factors of cirrhosis reversal and recompensation is still in the early stages.Here,we emphasize the reversibility of cirrhosis histologically and functionally.And we also discuss the potential mechanisms and diagnostic criteria for cirrhosis reversal and recompensation,summarize existing relevant study evidence,and present the urgent challenges in this field.

关 键 词：肝硬化 逆转 再代偿 机制 定义 

分 类 号：R575.2[医药卫生—消化系统]