Effect of the extrahepatic bile duct anatomy on choledocholithiasis and its clinical significance  

作　　者：Zheng Cao Jia Zhou Li Wei Hai-Yu He Jun Li 

机构地区：[1]Department of Gastroenterology,The Second Affiliated Hospital of Kunming Medical University,Kunming 650000,Yunnan Province,China

出　　处：《World Journal of Gastrointestinal Surgery》2024年第5期1363-1370,共8页世界胃肠外科杂志（英文版）（电子版）

基　　金：Kunming Medical University,No.2023S090.

摘　　要：BACKGROUND A comprehensive understanding of the extrahepatic bile duct anatomy is vital to guide surgical procedures and perform endoscopic retrograde cholangiography.Anatomical irregularities within the extrahepatic bile duct may increase susceptibility to bile duct stones.AIM To investigate the anatomical risk factors associated with extrahepatic bile ducts in patients diagnosed with choledocholithiasis,with a specific focus on preventing stone recurrence after surgical intervention and endoscopic lithotomy.METHODS We retrospectively analyzed the medical records of 124 patients without choledocholithiasis and 108 with confirmed choledocholithiasis who underwent magnetic resonance cholangiopancreatography examinations at our center between January 2022 and October 2022.Logistic regression analyses were conducted to identify the anatomical risk factors influencing the incidence of common bile duct stones.RESULTS Multivariate logistic regression analysis revealed that several factors independently contributed to choledocholithiasis risk.Significant independent risk factors for choledocholithiasis were diameter of the common hepatic[adjusted odds ratio(aOR)=1.43,95%confidence interval(CI):1.07-1.92,adjusted P value=0.016]and common bile(aOR=1.68,95%CI:1.27-2.23,adjusted P value<0.001)ducts,length of the common hepatic duct(aOR=0.92,95%CI:0.84-0.99,adjusted P value=0.034),and angle of the common bile duct(aOR=0.92,95%CI:0.89–0.95,adjusted P value<0.001).The anatomical features of the extrahepatic bile duct were directly associated with choledocholithiasis risk.Key risk factors include an enlarged diameter of the common hepatic and bile ducts,a shorter length of the common hepatic duct,and a reduced angle of the common bile duct.

关 键 词：Bile ducts EXTRAHEPATIC CHOLEDOCHOLITHIASIS CHOLANGIOPANCREATOGRAPHY Magnetic resonance CHOLANGIOPANCREATOGRAPHY Endoscopic retrograde 

分 类 号：R575.7[医药卫生—消化系统]