Advancements in breath-based diagnostics for pancreatic cancer:Current insights and future perspectives  

作　　者：Mesut Tez Eda Sahingoz Huseyin Fahri Martli 

机构地区：[1]Department of Surgery,University of Health Sciences,Ankara City Hospital,Ankara 06800,Türkiye [2]Department of General Surgery,Saglik Bilimleri University,Ankara 06100,Turkiye [3]Department of General Surgery,Ankara City Hospital,Ankara 06100,Türkiye

出　　处：《World Journal of Gastrointestinal Oncology》2024年第6期2300-2303,共4页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Recent decades have seen a concerning surge in carcinogenic diseases,with cancer cases and deaths on the rise globally.Conventional diagnostic methods are often invasive and time-consuming,highlighting the need for fast,accurate,and painless alternatives.Non-invasive exhaled breath analysis emerges as a promising solution,with over 200 volatile organic compounds(VOCs)detected in exhaled air,showing potential as biomarkers for various diseases,including cancer.Despite the lack of standardized methodologies,advancements in analytical instruments have expanded detection capabilities,reaching 3500 VOCs.Studies have identified specific VOC patterns associated with different cancers,offering hope for non-invasive diagnosis.Techniques such as gas chromatography-mass spectrometry and electronic noses show promise in distinguishing between healthy individuals and cancer patients.However,further research and standardization are needed to realize the full clinical potential of breath-based diagnostics,particularly in the early detection of challenging cancers like pancreatic cancer.

关 键 词：PANCREAS Volatile organic compounds Diagnosis Cancer BREATH 

分 类 号：R735.34[医药卫生—肿瘤]