Still elusive: Developments in the accurate diagnosis of indeterminate biliary strictures  

作　　者：Lynn Affarah Philip Berry Sreelakshmi Kotha 

机构地区：[1]Department of Hepatology,Guy's and St Thomas'Hospital,London SE17EH,United Kingdom

出　　处：《World Journal of Gastrointestinal Endoscopy》2024年第6期297-304,共8页世界胃肠内镜杂志（英文版）（电子版）

摘　　要：Indeterminate biliary strictures pose a significant diagnostic dilemma for gastroenterologists.Despite advances in endoscopic techniques and instruments,it is difficult to differentiate between benign and malignant pathology.A positive histological diagnosis is always preferred prior to high risk hepatobiliary surgery,or to inform other types of therapy.Endoscopic retrograde cholangiopancreato-graphy with brushings has low sensitivity and despite significant improvements in instruments there is still an unacceptably high false negative rate.Other methods such as endoscopic ultrasound and cholangioscopy have improved diagnostic quality.In this review we explore the techniques available to aid accurate diagnosis of indeterminate biliary strictures and obtain accurate histology to facilitate clinical management.

关 键 词：Indeterminate biliary stricture Benign biliary stricture Malignant biliary stricture Endoscopic retrograde cholangiopancreatography Endoscopic ultrasound Primary sclerosing cholangitis 

分 类 号：R575.7[医药卫生—消化系统]