Downstaging strategies for unresectable hepatocellular carcinoma  

作　　者：Georgia Sofia Karachaliou Nikolaos Dimitrokallis Dimitrios P Moris 

机构地区：[1]Division of Gastroenterology,Department of Medicine,Duke University Medical Center,Durham,NC 27710,United States [2]First Department of Surgery&Organ Transplant Unit,Evangelismos General Hospital,Athens 10676,Greece [3]Department of Surgery,Duke University Medical Center,Durham,NC 27710,United States

出　　处：《World Journal of Gastroenterology》2024年第20期2731-2733,共3页世界胃肠病学杂志（英文版）

摘　　要：A significant number of patients with hepatocellular carcinoma(HCC)are usually diagnosed in advanced stages,that leads to inability to achieve cure.Palliative options are focusing on downstaging a locally advanced disease.It is wellsupported in the literature that patients with HCC who undergo successful conversion therapy followed by curative-intent surgery may achieve a significant survival benefit compared to those who receive chemotherapy alone or those who are successfully downstaged with conversion therapy but not treated with surgery.Hepatic artery infusion chemotherapy can be a potential downstaging strategy,since recent studies have demonstrated excellent outcomes in patients with colorectal liver metastatic disease as well as primary liver malignancies.

关 键 词：Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy DOWNSTAGING Hepatocellular carcinoma 

分 类 号：R735.7[医药卫生—肿瘤]