Fifty-five cases of hepatic alveolar echinococcosis combined with lymph node metastasis:A retrospective study  

作　　者：Yilizhati Aimaitijiang Tie-Min Jiang Ying-Mei Shao Tuerganaili Aji 

机构地区：[1]State Key Laboratory on Pathogenesis,Prevention and Treatment of High Incidence Diseases in Central Asia,The First Clinical College,Xinjiang Medical University,Urumqi 830011,Xinjiang Uygur Autonomous Region,China [2]The First Ward of Hepatobiliary and Pancreatic Surgery,Tumor Hospital Affiliated to Xinjiang Medical University,Urumqi 830011,Xinjiang Uygur Autonomous Region,China [3]Department of Hepatobiliary&Hydatid Diseases,Digestive&Vascular Surgery Center,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang Uygur Autonomous Region,China [4]Xinjiang Clinical Research Center for Echinococcosis and Hepatobiliary Diseases,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,Xinjiang Uygur Autonomous Region,China

出　　处：《World Journal of Gastroenterology》2024年第23期2981-2990,共10页世界胃肠病学杂志（英文版）

基　　金：Supported by Natural Science Foundation of Xinjiang Uygur Autonomous Region,China,No.2022D01D17.

摘　　要：BACKGROUND Lymph node metastasis is a specific type of metastasis in hepatic alveolar echinococcosis(AE).Currently,there is a scarcity of describing the clinical characteristics and lymph node metastasis rules of patients with hepatic AE combined with lymph node metastasis and its mechanism and management are still controversial.Radical hepatectomy combined with regional lymph node dissection is a better treatment.AIM To analyse the clinical features of hepatic AE combined with lymph node metastasis to explore its treatment and efficacy.METHODS A total of 623 patients with hepatic AE admitted to the First Affiliated Hospital of Xinjiang Medical University from 1 January 2012 to 1 January 2022 were retrospectively analysed.Fifty-five patients with combined lymph node metastasis were analysed for their clinical data,diagnosis and treatment methods,follow-up efficacy,and characteristics of lymph node metastasis.Finally,we comparatively analysed the lymph node metastasis rates at different sites.Categorical variables are expressed as frequencies and percentages,and the analysis of difference was performed using theχ2 test.The Bonferroni method was used for pairwise comparisons when statistical differences existed between multiple categorical variables.RESULTS A lymph node metastasis rate of 8.8%(55/623)was reported in patients with hepatic AE,with a female predilection(69.1%)and a statistically significant sex difference(χ2=8.018,P=0.005).Of the 55 patients with lymph node metastasis,72.7%had a parasite lesion,neighbouring organ invasion,and metastasis stage of P3N1M0 and above,of which 67.3%,78.2%,and 34.5%of hepatic AE lesions invaded the bile ducts,blood vessels,and distant metastases,respectively.Detection rates of lymph node metastasis of 16.4%,21.7%,and 34.2%were reported for a preoperative abdominal ultrasound,magnetic resonance imaging,and computed tomography examinations.All patients were intraoperatively suspected with enlarged lymph nodes and underwent radical hepatectomy combined with regional lymph nod

关 键 词：ECHINOCOCCOSIS Radical hepatectomy Lymph node metastasis Lymph node dissection Alveolar echinococcosis HEPATIC 

分 类 号：R735.37[医药卫生—肿瘤]