肝细胞癌合并门静脉癌栓患者术后癌症复发恐惧现状及其影响因素分析  

Analysis of the Status of after Operation Fear of Cancer Recurrence and the Influencing Factors in Patients with Hepatocellular Carcinoma and Portal Vein Tumor Thrombus

作　　者：詹元 刘怡素 谭朝霞[2] 易湘兰[2] 谭小兰 陈亚莉 ZHAN Yuan;LIU Yi-su;TAN Chao-xia;YI Xiang-lan;TAN Xiao-lan;CHEN Ya-li(Medical College of Hunan Normal University,Changsha,Hunan,410205,China;Department of Hepatobiliary Surgery,Hunan Provincial People's Hospital,Changsha,Hunan,410000,China)

机构地区：[1]湖南师范大学医学院,湖南长沙410205 [2]湖南省人民医院肝胆外科,湖南长沙410000

出　　处：《现代生物医学进展》2024年第8期1505-1510,1534,共7页Progress in Modern Biomedicine

基　　金：湖南省自然科学基金项目(2020JJ8085)。

摘　　要：目的:探讨肝细胞癌(HCC)合并门静脉癌栓(PVTT)患者术后癌症复发恐惧(FCR)现状并分析其影响因素。方法:选取2018年1月~2022年12月在湖南省人民医院行手术切除的105例HCC合并PVTT患者,采用一般资料调查表收集患者临床资料,中文版癌症复发恐惧量表(FCRI-CV)评价HCC合并PVTT患者FCR。采用单因素和多元线性回归模型分析HCC合并PVTT患者FCR的影响因素。结果:105例HCC合并PVTT患者FCRI-CV评分平均得分(91.54±11.74)分。单因素分析显示,年龄、距离确诊时间、美国东部肿瘤协作组(ECOG)功能状态评分、文化程度、婚姻状况、工作状况、家庭年收入、医疗付费方式、主要照顾者为HCC合并PVTT患者FCR的影响因素(P<0.05)。多元线性回归模型分析显示:年龄≥75岁、距离确诊时间>12个月、文化程度大专及以上、工作状况在职和下岗、家庭年收入>100000元、自费医疗是HCC合并PVTT患者FCR的独立影响因素(P<0.05)。结论:HCC合并PVTT患者FCR处于中上水平,与年龄、距离确诊时间、文化程度、工作状况、家庭年收入和医疗付费方式有关。Objective:To investigate the status of after operation fear of cancer recurrence(FCR)and the influencing factors in patients with hepatocellular carcinoma(HCC)and portal vein tumor thrombus(PVTT).Methods:105 HCC patients with PVTT who underwent surgical resection in Hunan Provincial People's Hospital from January 2018 to December 2022 were selected,the clinical data of patients were collected by using a general data questionnaire,and FCR in HCC patients with PVTT were evaluated by Chinese version of the fear of cancer recurrence scale(FCRI-CV).The influencing factors of FCR in HCC patients with PVTT were analyzed by univariate and multivariate linear regression models.Results:The average FCRI-CV score of 105 HCC patients with PVTT was(91.54±11.74).Univariate analysis showed that age,distance from diagnosis time,Eastern Cooperative Oncology Group(ECOG)functional status score,education level,marital status,working status,family annual income,medical payment method and primary caregiver were the influencing factors of FCR in HCC patients with PVTT(P<0.05).Multivariate linear regression model analysis showed that,age≥75 years old,distance from diagnosis time>12 months,education level was college degree or above,working status was on-the-job and off-the-job,family annual income>100,000 yuan,self-paid medical treatment were independent influencing factors of FCR in HCC patients with PVTT(P<0.05).Conclusion:FCR in HCC patients with PVTT was in upper middle level,which was relate to age,distance from diagnosis time,education level,working status,family annual income and medical payment method.

关 键 词：肝细胞癌 门静脉癌栓 癌症复发恐惧 影响因素 

分 类 号：R735.7[医药卫生—肿瘤]