介入治疗破裂小型颅内动脉瘤的效果观察及安全性评价  

Efficacy and safety of interventional treatment of small ruptured intracranial aneurysms

作　　者：刘树燊 李晓伟 蔺晓龙 LIU Shu-shen;LI Xiao-wei;LIN Xiao-long(Department of Neurosurgery,Feicheng Hospital of Shandong Yiyang Health group,Taian 271608,China)

机构地区：[1]山东颐养健康集团肥城医院神经外科,271608 [2]山东颐养健康集团肥城医院心内科,271608

出　　处：《中国实用医药》2024年第11期11-15,共5页China Practical Medicine

摘　　要：目的 探究破裂小型颅内动脉瘤患者接受介入治疗的效果。方法 70例小型颅内动脉瘤患者,按照颅内动脉瘤是否破裂分为对照组(未破裂)和观察组(破裂),每组35例。两组患者均接受介入治疗。比较两组患者治疗前后的神经功能情况(格拉斯哥昏迷量表、格拉斯哥预后量表、改良Rankin量表评分)、日常生活能力、生活质量以及术后即刻动脉瘤栓塞程度、术后半年动脉瘤栓塞程度、并发症发生情况。结果 观察组患者治疗后格拉斯哥昏迷量表评分(10.05±1.16)分、格拉斯哥预后量表评分(4.25±0.50)分、改良Rankin量表评分(1.50±0.25)分均优于对照组的(8.73±1.07)、(4.00±0.25)、(1.75±0.25)分(P<0.05)。观察组患者治疗后的生理机能评分(88.32±3.57)分、躯体疼痛评分(90.26±3.17)分、精神健康评分(89.21±3.25)分、社会功能评分(89.85±2.58)分均优于对照组的(81.63±3.61)、(82.69±2.24)、(83.55±3.58)、(83.44±3.67)分(P<0.05)。观察组患者术后即刻动脉瘤栓塞程度优于对照组(P<0.05)。两组患者日常生活能力评分、术后半年动脉瘤栓塞程度、并发症发生率均不存在显著差异(P>0.05)。结论 破裂小型颅内动脉瘤患者接受介入治疗具有较高的临床效果以及安全性。Objective To explore the effect of interventional therapy on patients with small ruptured intracranial aneurysms.Methods A total of 70 patients with small ruptured intracranial aneurysms were divided into control group(unruptured)and observation group(ruptured)according to whether the intracranial aneurysm ruptured,with 35 cases in each group.Both groups received interventional therapy.Patients in both groups were compared in terms of neurological function(scores of Glasgow Coma Scale,Glasgow Outcome Scale,modified Rankin Scale),activities of daily living and quality of life before and after treatment,aneurysm embolization immediately after surgery,aneurysm embolization 6 months after surgery,and occurrence of complications.Results After treatment,the scores of Glasgow Coma Scale,Glasgow Outcome Scale,and modified Rankin Scale were(10.05±1.16),(4.25±0.50)and(1.50±0.25)points in observation group,which were better than(8.73±1.07),(4.00±0.25)and(1.75±0.25)points in the control group(P<0.05).After treatment,the physiological function score of the observation group was(88.32±3.57)points,the bodily pain score was(90.26±3.17)points,the mental health score was(89.21±3.25)points,and the social function score was(89.85±2.58)points,which were better than(81.63±3.61),(82.69±2.24),(83.55±3.58),and(83.44±3.67)points of the control group(P<0.05).The status of aneurysm embolization immediately after surgery of patients in the observation group was better than that in the control group(P<0.05).There was no significant difference in the activities of daily living score,aneurysm embolization 6 months after surgery,and the incidence of complications between the two groups(P>0.05).Conclusion Interventional treatment of patients with small ruptured intracranial aneurysms has a high clinical outcome and safety.

关 键 词：介入治疗 破裂小型颅内动脉瘤 低分子肝素盐水 安全性 

分 类 号：R743[医药卫生—神经病学与精神病学]